Dietary Antioxidants in the Mediterranean Diet

Barbouti, Alexandra; Goulas, Vlasios

doi:10.3390/antiox10081213

Cited by 14 publications

(14 citation statements)

References 30 publications

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“…The beneficial health effects of the Mediterranean diet have been often assigned to antioxidants. 33 A recent study also indicated that omega-3 PUFAs intake had antioxidative effects. 12 Furthermore, it has been assumed that dietary antioxidants protect cells and tissues from oxidation and prevent or delay the development of several diseases.…”

Section: Discussionmentioning

confidence: 98%

Does Dietary Polyunsaturated Fatty Acid Intake Associate With Bone Mineral Density and Limb Structural Changes in Early Rheumatoid Arthritis?

Valner

Müller

Kull³

et al. 2023

Nutr Metab Insights

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Background: Rheumatoid arthritis (RA) is an inflammatory disease that can result in bone erosion, lean mass lowering, and increase of fat mass without changes in body weight. The dietary consumption of polyunsaturated fatty acids (PUFAs) has been assessed in many studies due to their potential anti-inflammatory effect. Aim: The aim of this research was to identify if dietary intake of PUFAs associates with bone mineral density (BMD) and limb structural changes in early rheumatoid arthritis (ERA) compared to a population-based control group. The study was conducted because previous results have been insufficient. Methods: The study group consisted of 83 ERA patients and 321 control subjects. A dual-energy X-Ray absorptiometry (DXA) machine was used to measure hip, lumbar spine, and radius BMD, as well as arm and leg fat, lean, and bone mass. Dietary habits and inflammatory markers were assessed to evaluate the effects to BMD and limb structural changes. Results: In ERA subjects, higher dietary consumption of PUFAs was associated with a decrease in arm fat mass (b −28.17, P = .02) and possibly with higher lumbar BMD (b 0.008, P = .058). Limb bone and lean mass changes were not associated with dietary intake of PUFAs. Conclusion: Balanced nutrition is essential. Consuming PUFAs could be beneficial in ERA preventing structural changes to hands, but additional research is needed.

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Section: Discussionmentioning

confidence: 98%

Does Dietary Polyunsaturated Fatty Acid Intake Associate With Bone Mineral Density and Limb Structural Changes in Early Rheumatoid Arthritis?

Valner

Müller

Kull³

et al. 2023

Nutr Metab Insights

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“…The Mediterranean diet supplies a plethora of vitamins (e.g., β-carotene, vitamin C, vitamin E), minerals, and polyphenols, with antioxidant, anti-inflammatory, and pro-autophagic properties [ 67 , 70 , 71 , 72 ]. For instance, the PREvencion con DIeta MEDiterranea (PREDIMED) study found a decrease in inflammatory biomarkers, such as interleukin 6, C-reactive protein, and leukocyte adhesion molecules, in participants with higher Mediterranean diet adherence [ 73 ].…”

Section: Discussionmentioning

confidence: 99%

Low Adherence to Mediterranean Diet Is Associated with Probable Sarcopenia in Community-Dwelling Older Adults: Results from the Longevity Check-Up (Lookup) 7+ Project

et al. 2023

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Muscle strength is a relevant metric of aging. Greater adherence to Mediterranean diet is associated with better health outcomes across all life stages; however, evidence on the relationship between Mediterranean diet and muscle strength in older adults is inconclusive. In this study, we evaluated the relationship between adherence to Mediterranean diet and handgrip strength in a large sample of community-dwelling older adults from the Longevity Check-up 7+ project. A total of 2963 participants (mean age 72.8 ± 5.7 years; 54.4% women) were analyzed. Mediterranean diet adherence was evaluated using a modified Medi-Lite score and categorized as low (≤8), good (9 to 11), or high (≥12). Handgrip strength was categorized as normal or low according to cut-points by the European Working Group on Sarcopenia in Older People 2. Older adults with lower Mediterranean diet adherence had a significantly higher prevalence of probable sarcopenia (25.9%) than those with good (19.1%) or high (15.5%) adherence. The proportion of participants with probable sarcopenia increased with age, but it remained lower in the good and high adherence groups. Logistic regression showed that greater Mediterranean diet adherence was associated with a lower risk of probable sarcopenia. Older age, female sex, and physical inactivity were associated with a greater risk of probable sarcopenia. Our findings emphasize the positive association between healthy lifestyles, including adherence to Mediterranean diet, and physical function in old age.

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“…There is a wealth of published data for identifying and quantitatively determining phenolic constituents in Thymus plant extracts [ 175 , 176 , 177 , 178 , 179 , 180 , 181 , 182 ]. They have been widely investigated for their biological activities in physiological systems, e.g., antioxidant, anti-aging, anticarcinogenic, pro-apoptosis, anti-inflammation, and anti-atherosclerosis.…”

Section: Thymus Algeriensis Boiss and Reutmentioning

confidence: 99%

Thymus hirtus Willd. ssp. algeriensis Boiss. and Reut: A Comprehensive Review on Phytochemistry, Bioactivities, and Health-Enhancing Effects

Lahlou

Samba

Soeiro

et al. 2022

Foods

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Members of the Lamiaceae family are considered chief sources of bioactive therapeutic agents. They are important ornamental, medicinal, and aromatic plants, many of which are used in traditional and modern medicine and in the food, cosmetic, and pharmaceutical industries. In North Africa, on the Mediterranean side, there is the following particularly interesting Lamiaceous species: Thymus hirtus Willd. sp. Algeriensis Boiss. Et Reut. The populations of this endemic plant are distributed from the subhumid to the lower arid zone and are mainly employed as ethnomedicinal remedies in the following Maghreb countries: Algeria, Libya, Morocco, and Tunisia. In fact, they have been applied as antimicrobial agents, antispasmodics, astringents, expectorants, and preservatives for several food products. The species is commonly consumed as a tea or infusion and is used against hypercholesterolemia, diabetes, respiratory ailments, heart disease, and food poisoning. These medicinal uses are related to constituents with many biological characteristics, including antimicrobial, antioxidant, anticancer, anti-ulcer, anti-diabetic, insecticidal, and anti-inflammatory activities. This review aims to present an overview of the botanical characteristics and geographical distribution of Thymus algeriensis Boiss. Et Reut and its traditional uses. This manuscript also examines the phytochemical profile and its correlation with biological activities revealed by in vitro and in vivo studies.

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Dietary Antioxidants in the Mediterranean Diet

Abstract: Epidemiological studies performed during the second half of the previous century have correlated the diet that prevailed in the north shores of the Mediterranean basin with beneficial health effects, including reduced mortality risk and lower incidences of cardiovascular diseases [...]

Cited by 14 publications

References 30 publications

Does Dietary Polyunsaturated Fatty Acid Intake Associate With Bone Mineral Density and Limb Structural Changes in Early Rheumatoid Arthritis?

Does Dietary Polyunsaturated Fatty Acid Intake Associate With Bone Mineral Density and Limb Structural Changes in Early Rheumatoid Arthritis?

Low Adherence to Mediterranean Diet Is Associated with Probable Sarcopenia in Community-Dwelling Older Adults: Results from the Longevity Check-Up (Lookup) 7+ Project

Thymus hirtus Willd. ssp. algeriensis Boiss. and Reut: A Comprehensive Review on Phytochemistry, Bioactivities, and Health-Enhancing Effects

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