Dietary Anti-nutritional Factors and Their Roles in Livestock Nutrition

Hafsa, Salma H. Abu; Hassan, A. A.; Elghandour, Mona M.Y.; Barbabosa‐Pliego, Alberto; Mellado, Miguel; Salem, Abdelfattah Z. M.

doi:10.1007/978-3-031-07496-7_4

Cited by 2 publications

(1 citation statement)

References 142 publications

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“…PIs commonly found in raw legume seeds are trypsin and chymotrypsin inhibitors ( 44 ). Trypsin inhibitors (TIs) have been connected to increased pancreatic secretory activity, increased pancreatic hypertrophy, and decreased protein digestibility.…”

Section: Introductionmentioning

confidence: 99%

A review on anti-nutritional factors: unraveling the natural gateways to human health

Salim,

Nehvi,

Mir

et al. 2023

Front. Nutr.

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Humans are constantly facing multiple health challenges from both communicable and non-communicable diseases that significantly affect their health. Additionally, drug resistance or failure has made the situation even worse and poses serious challenges for researchers to develop new drugs. Hence, to address these problems, there is an urgent need to discover and develop timely and long-term-based therapeutic treatments from different sources. One such approach is harnessing the potential of plant secondary metabolites. Plants have been utilized for therapeutic purposes in addition to being used for nutritional benefits. In the last two decades, plant-based drug developments have been one of the effective means of treating human diseases owing to their multiple functions. More recently, anti-nutritional factors (ANFs) have emerged as one of the important targets for novel plant-based drug development due to their multifaceted and potential pharmacological properties. However, their anti-nutritional properties have been the major setback for their limited success in the pharmacological sector. In this review, we provide an overview of ANFs and their beneficial roles in preventing human diseases with multiple case studies. We also highlight the recent developments and applications of ANFs in the food industry, agriculture, and pharmaceutics with future perspectives. Furthermore, we evaluate meta-analyses on ANFs from the last 30 years in relation to their function in human health benefits. This review is an endeavor to reevaluate the merit of these natural compounds and explore their potential for both human and animal health.

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Section: Introductionmentioning

confidence: 99%

A review on anti-nutritional factors: unraveling the natural gateways to human health

Salim,

Nehvi,

Mir

et al. 2023

Front. Nutr.

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In vitro Gas production and rumen fermentation for rations containing increasing levels of Panicum maximum cv. Mombasa with or without Spirulina

meteab,

Khorshed,

El-Essawy

et al. 2024

Preprint

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This study aimed to evaluate the impact of replacing alfalfa hay with Panicum maximum hay, with or without ascending levels of Spirulina supplementation on in-vitro gas production and fermentation parameters. Isocaloric and isonitrogenous experimental diets were formulated to contain 40% roughage + 60 % concentrate, ascending replacement with Panicum maximum hay at levels 0, 25%, 50%, 75%, and 100% take place in rations R1, R2, R3, R4, and R5, respectively. Each ration supplemented with incremental levels 0, 0.5, 1.5, 2, 2.5, and 3kg spirulina per Ton of feed. Results indicated that the potential of gas production after 24 h was linearly increased by increasing the level of Spirulina. The control group (R1) recorded the highest values of gas production, while it was the lowest at (R5) (p<.0001). In vitro degradability of dry and organic matter was negatively affected by the increment of Panicum maximum and Spirulina levels and vice versa, until 2 kg/ton of Spirulina (p<.0001). The addition of Spirulina significantly (p<.0001) increased total volatile fatty acids (TVFA) and N-NH3 concentration, until 2Kg/ton, while the addition of Panicum maximum hay significantly increased N-NH3 concentration, until it reached at (R4). As a result, the best mixing ratio between Alfalfa and Panicum maximum hays was recorded at R2. In conclusion, the substitution of alfalfa hay with 25% Panicum maximum hay (R2) and incorporation of Spirulina as feed additive (2Kg/ton) could offer a good solution in dry periods to improve the quality of Panicum maximum and can be used to maximize degradability and ruminal fermentation parameters.

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Dietary Anti-nutritional Factors and Their Roles in Livestock Nutrition

Cited by 2 publications

References 142 publications

A review on anti-nutritional factors: unraveling the natural gateways to human health

A review on anti-nutritional factors: unraveling the natural gateways to human health

In vitro Gas production and rumen fermentation for rations containing increasing levels of Panicum maximum cv. Mombasa with or without Spirulina

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