Dietary administration of the probiotic SpPdp11: Effects on the intestinal microbiota and immune-related gene expression of farmed Solea senegalensis treated with oxytetracycline

Tapia‐Paniagua, Silvana; Vidal, Sara; Lobo, C.; Banda, Inés García de la; Esteban, M. Ángeles; Balebona, M.C.; Moriñigo, Miguel A.

doi:10.1016/j.fsi.2015.07.007

Cited by 40 publications

(26 citation statements)

References 105 publications

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“…Rashid et al ( 2014 ) suggested that probiotics VSL#3 protected rats from endothelial dysfunction in rats by down-regulating p47 phox expression. Tapia-Paniagua et al ( 2015 ) also reported that probiotic SpPdp11 decreased the NOX transcription in Solea senegalensis . However, in this study, Ba replacement didn’t alter NOX activity and p47 phox level in piglets.…”

Section: Discussionmentioning

confidence: 94%

Effects of probiotic Bacillus as a substitute for antibiotics on antioxidant capacity and intestinal autophagy of piglets

Wang

et al. 2017

AMB Expr

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The objective of this study was to evaluate effects of probiotic Bacillus amyloliquefaciens (Ba) as a substitute for antibiotics on growth performance, antioxidant ability and intestinal autophagy of piglets. Ninety piglets were divided into three groups: G1 (containing 150 mg/Kg aureomycin in the diet); G2 (containing 75 mg/Kg aureomycin and 1 × 108 cfu/Kg Ba in the diet); G3 (containing 2 × 108 cfu/Kg Ba in the diet without any antibiotics). Each treatment had three replications of ten pigs per pen. Results showed that Ba replacement significantly increased the daily weight gain of piglets. Moreover, improved antioxidant status in serum and jejunum was noted in Ba-fed groups as compared with aureomycin group. Increased gene expression of antioxidant enzymes and elevated nuclear factor erythroid 2 related factor 2 (Nrf2) in jejunum was also observed in Ba-fed groups. Besides, Ba replacement significantly decreased jejunal c-Jun N-terminal kinase (JNK) phosphorylation compared with antibiotic group. Western blotting results also revealed that replacing all antibiotics with Ba initiated autophagy in the jejunum as evidenced by increased microtubule-associated protein 1 light chain 3 II (LC3-II) abundance. Taken together, these results indicate that replacing aureomycin with Ba can improve growth performance and antioxidant status of piglets via increasing antioxidant capacity and intestinal autophagy, suggesting a good potential for Ba as an alternative to antibiotics in feed.Electronic supplementary materialThe online version of this article (doi:10.1186/s13568-017-0353-x) contains supplementary material, which is available to authorized users.

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Section: Discussionmentioning

confidence: 94%

Effects of probiotic Bacillus as a substitute for antibiotics on antioxidant capacity and intestinal autophagy of piglets

Wang

et al. 2017

AMB Expr

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“…At the genus level, Pseudomonas , Enterobacter and Stenotrophomonas were the most predominant genera, while Achromobacter and Luteibacter were less abundant. Enterobacter , Achromobacter and Pseudomonas have been described as some of the most dominant genera in marine fish (Parlapani & Boziaris, ; Tapia‐Paniagua et al, ; Wang, Zhang, Li, & Lin, ). Strains of these genera have shown to have positive effects on fish host due to their ability to degrade cellulose and even some Pseudomonas and Enterobacter strains have been proposed as probiotic bacteria (Nayak, ).…”

Section: Discussionmentioning

confidence: 99%

The effect of spray‐dried porcine plasma on gilthead seabream (Sparus aurata) intestinal microbiota

et al. 2020

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The effect of spray‐dried porcine plasma (SDPP) on the intestinal histological organization and autochthonous microbiota composition was evaluated in Sparus aurata. Fish were fed a basal diet (51 g/kg protein, 17 g/kg fat, 20.6 MJ/kg gross energy) and a diet containing 3 g/kg SDPP for 95 days (initial body weight, BW = 9.5 ± 0.2g, mean ± SD). The inclusion of SDPP promoted growth (p < .05), being fish fed the SDPP diet 6.2% (BW = 88.2 ± 1.6 g) heavier than the control (BW = 82.7 ± 3.2 g). SDPP increased the density of intestinal goblet cells (p < .05), whereas no differences in villi height were found (p > .05) between both groups. Intestinal microbiota was dominated by Proteobacteria (>85%) and Firmicutes (5%–12%), whereas Bacteroidetes never represented more than 1.5%. γ‐Proteobacteria, and Bacilli and Clostridia were the predominant classes. The short administration of SDPP (20 days) resulted in changes in microbiota diversity and richness associated with an increase in the sequences of the genus Lactobacillus and to a decrease in the genus Vibrio, whereas these changes were reverted at 95 days. Intestinal goblet cell density was not correlated to microbiota diversity and richness changes rather than to the immunostimulatory effect of the SDPP.

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“…The present results are in agreement with these studies, and such an immunosuppressive effect of OTC might be as a result of deposition in lymphoid and hepatic tissues causing improper immune function (Rodrigues et al, ; Yonar et al, ), as OTC was reported to have efficient tissue penetration (Björklund & Bylund, ). On the other hand, antibiotics including OTC decrease intestinal microbiota diversity and frequency (Bakke‐McKellep et al, ; Navarrete, Mardones, Opazo, Espejo, & Romero, ; Tapia‐Paniagua et al, ), which may decrease immune function, as intestinal microbiota has a significant role in immune response in fish (Gómez & Balcázar, ). Seemingly, thyme treatment was efficient to inhibit OTC‐induced immunosuppression, as the suppressed WBC, neutrophil, total Ig levels and lysozyme and ACH50 activity were restored by thyme treatment.…”

Section: Discussionmentioning

confidence: 99%

Beneficial effects of thyme (Thymus vulgaris) extract on oxytetracycline-induced stress response, immunosuppression, oxidative stress and enzymatic changes in rainbow trout (Oncorhynchus mykiss)

Hoseini

Yousefi

2018

Aquacult Nutr

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The aim of the present study was to investigate the effects of thyme extract (TE) and oxytetracycline (OTC) on rainbow trout (Oncorhynchus mykiss) stress response, immune parameters, oxidative stress and enzymatic changes. The fish were assigned into eight treatments receiving diets with OTC (0 and 2.5 g/kg) and TE (0, 5, 10 and 20 g/kg) for 2 weeks. Thereafter, serum characteristics and gut oxidative status were evaluated. OTC significantly increased serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activities, and cortisol and glucose levels; however, TE significantly suppressed these changes. OTC significantly decreased, but TE significantly increased gut catalase (CAT) and glutathione peroxidase (GPx) activities.OTC significantly decreased gut superoxide dismutase (SOD) and increased gut glutathione-s-transferase (GST) activities, malondialdehyde (MDA) content and blood monocyte percentage; TE significantly mitigated these changes. TE significantly increased serum total protein, total Ig, lysozyme and ACH50, and blood WBC; however, OTC significantly decreased serum lysozyme and ACH50 activities and blood WBC and neutrophil percentage. In conclusion, OTC administration causes immunosuppression, which might be related to deterioration of fish health. TE augments trout innate immune and antioxidant status and is capable to counteract OTC-induced health and immune deterioration. K E Y W O R D Shealth, innate immune, oxytetracycline, thyme, trout | 299 HOSEINI aNd YOUSEFI

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Dietary administration of the probiotic SpPdp11: Effects on the intestinal microbiota and immune-related gene expression of farmed Solea senegalensis treated with oxytetracycline

Cited by 40 publications

References 105 publications

Effects of probiotic Bacillus as a substitute for antibiotics on antioxidant capacity and intestinal autophagy of piglets

Effects of probiotic Bacillus as a substitute for antibiotics on antioxidant capacity and intestinal autophagy of piglets

The effect of spray‐dried porcine plasma on gilthead seabream (Sparus aurata) intestinal microbiota

Beneficial effects of thyme (Thymus vulgaris) extract on oxytetracycline-induced stress response, immunosuppression, oxidative stress and enzymatic changes in rainbow trout (Oncorhynchus mykiss)

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