Diet-Related Disease, Nutritional Genomics, and Food and Nutrition Professionals

DeBusk, Ruth

doi:10.1016/j.jada.2008.11.037

Cited by 22 publications

(6 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Whether such practice will be feasible for the population-at-large in the immediate future remains to be determined, but the principles and tools of Nutrigenomics are expected to soon allow for earlier and more targeted interventions than currently exist [69]. As the current research in Nutrigenomics often focuses on how diet-gene interactions influence phenotypes found to be predictive biomarkers of disease [70,71], it is likely that the path from research to applications will proceed into clinical practice using these markers of chronic disease as outcome measures.…”

Section: Nutrigenomics and Biomarkers Developmentmentioning

confidence: 99%

Nutrigenomics: The Science to Unfold the Impact of GM Food on Health

Gupta¹

2018

FSNT

View full text Add to dashboard Cite

After the development of second generation transgenic crops, molecular characterization of food and feed and its impact on health became imperative. The growing awareness towards the impact of modified food or diet on human health led down the foundation of nutrigenomics. Nutrigenomics is an emerging field of science that tends to unfold the role of nutrition on gene expression which brings together the science of bioinformatics, nutrition, molecular biology, genomics, epidemiology and molecular medicine. The present review focuses on origin, status, strategies and goals of Nutrigenomics research. Omics supported different techniques, which have been considered as the best research tools to study the effect of diet/ food on the genome, are also discussed in relation to Nutrigenomics. To gain deeper insight of diet-gene interaction and to develop biomarker for early prediction of diet related diseases, there is an urgent need to boost more research in the field of Nutrigenomics to help people in understanding the relationship between diet and health.

show abstract

Section: Nutrigenomics and Biomarkers Developmentmentioning

confidence: 99%

Nutrigenomics: The Science to Unfold the Impact of GM Food on Health

Gupta¹

2018

FSNT

View full text Add to dashboard Cite

show abstract

“…Fortunately, we are just beginning a new revolution in biology called personalized medicine, [29][30][31][32][33] which includes nutritional genomics. [34][35][36][37][38][39][40][41][42][43][44] Nutritional genomics utilizes whole genome sequencing, gene expression, and DNA methylation technologies to best define the optimal medicine or diet to maximize human health. A medicine or diet will soon be customized for the individual based on his or her genome sequence.…”

Section: History Of Treating the Diabetic Populationmentioning

confidence: 99%

Personalized nutrigenomics: tailoring the diet to the aging diabesity population

Ruden

Lu²

2011

NDS

View full text Add to dashboard Cite

According to the International Diabetes Federation (IDF), 190 million people worldwide suffer from diabetes, and this number is estimated to double by the year 2025. Diabetes is especially prominent in the elderly population because the IDF indicates age above 45 years as a major risk factor for diabetes. The most common trials for controlling diabetes focus on tighter glucose control as a means to reduce the long-term complications. However, whether tight blood sugar control or other dietary or pharmaceutical interventions in the elderly are more appropriate is not known. Major changes have taken place in our diet over the past 10,000 years since the beginning of the Agricultural Revolution, but our genes have not changed. Furthermore, the large numbers of diabetic elderly in the population are a recent phenomenon, because those with diabetes have historically died young. Genetically speaking, humans today live in a nutritional environment that differs from that for which our genetic constitution was selected. For example a high omega-6/omega-3 ratio, found in today's Western diets, promotes the pathogenesis of many chronic diseases, including cardiovascular disease and diabetes. Knowing who is at risk would be useful if it meant that one could avoid the environmental triggers that convert susceptibility to disease. The prospect of targeting specific dietary treatments at the elderly, who are predicted to gain the most therapeutic benefits, clearly has important clinical and economic consequences. In this review, we will discuss modern molecular genetic and epidemiological techniques which are now, or soon will be, made available by inexpensive whole-genome sequencing and other whole genome approaches to treat the elderly diabetic population.

show abstract

“…Five areas have been identified by international experts [6] in the context of both basic nutrigenomics research and its clinical and commercial uses: (1) health claims benefits arising from nutrigenomics, (2) managing nutrigenomics information, (3) delivery methods of nutrigenomics services, (4) nutrigenomics products and (5) equitable accessibility to nutrigenomics. Hence, it is important to elevate the depth of debate to understand and management of this 'biohype' on dietgene interactions using evidence-based research methodologies [7,8].…”

Section: Commercial Application Of Nutrigenomicsmentioning

confidence: 99%

Personalised food: how personal is it?

Ghosh¹

2009

Genes Nutr

View full text Add to dashboard Cite

Consumer goods became increasingly personalised, particularly during the last half of the 20th century. Foods and food products have been added a new flavour in this consumer trends with increasingly personalised values of convenience, cost, packaging, and taste. Now functional food industry is ready to take its next venture in a relatively new domain personalising health. Whether the goal of matching foods to individual genotypes to improve the health of those individuals can be attained, and personalised nutrigenomic foods enter the world's food markets, depends on numerous hurdles being overcome: some scientific in nature, some technical and others related to consumer, market or ethical issues. Public adoption of new technologies is an important determinant for their success. Many of the drivers behind the trend in personalisation of food are now known, particularly ethical, legal and social issues (ELSI) are the major drivers. Future development in the field of nutrigenomics undoubtedly will place its seemingly huge potential in better perspective. Thus, the agriculture and food enterprise has an extraordinary opportunity to link individuals with foods that are personalised for their health.

show abstract

Diet-Related Disease, Nutritional Genomics, and Food and Nutrition Professionals

Cited by 22 publications

References 14 publications

Nutrigenomics: The Science to Unfold the Impact of GM Food on Health

Nutrigenomics: The Science to Unfold the Impact of GM Food on Health

Personalized nutrigenomics: tailoring the diet to the aging diabesity population

Personalised food: how personal is it?

Contact Info

Product

Resources

About