Diet, nutrition and inflammatory bowel disease

Cooked navy and black bean diets improve biomarkers of colon health and reduce inflammation during colitis

“…In summary, dietary incorporation of whole cooked beans improved the DSS-induced colitis phenotype by reducing inflammatory mediator expression both locally within the inflamed colon and systemically, an effect attributable to the bean bioactive components, namely fermentation-derived SCFA and/or phenolic compounds. The amount of evidence supporting an anti-inflammatory role of diet-derived bioactives and extracts is increasing ( 132 , 133 ) ; however, there is a lack of information regarding the impact of consuming whole foods. In the present study, whole beans were cooked in the same manner as commonly prepared domestically, thereby providing an additional advantage when translating the outcomes to the clinical setting.…”

Inflammatory bowel disease: review and future view

“…The interrelationships between IBD and diet are complex, and are an area of great interest and confusion among both physicians and patients. There are a great deal of objective data outlining the nutritional complications caused by IBD, but in the area of cause or cure, information is sparse, anecdotal and often conflicting (5). The rise in the incidence and the prevalence of IBD has paralleled the social and economic development of populations and adaptation to a Western lifestyle that include diet changes, smoking, oral contraceptives and stress (46).…”

“…Attempting to isolate single nutrients or even patterns of nutrient intake is a daunting task, fraught with potential methodological pitfalls. Although evidence is far from definite, certain recurrent themes emerge (5).…”

“…Also, a change in diet may alter the bacterial flora increasing recognition that the intestinal flora may have an important role in the enthusiasm for probiotic therapy, role of prebiotics are a well-accepted mechanism of modulating the intestinal flora. Finally, dietary modification may alter intestinal fluid transport and gas production, minimizing symptoms, but has no direct effect on the disease itself (5). Eicosapentaenoic acid (EPA) derived from fish oil inhibits leukotriene activity.…”

“…It has been hypothesized that complete healing of the intestinal mucosa in inflammatory bowel diseases should result in reduced disease complications, reduced hospitalization and reduced surgical treatment (4). Diet is one of the most frequently discussed points and interrelationships between IBD and diet are complex and are an area of great interest and confusion among both physicians and patients (5). The interaction of food and the GI mucosal immune system is an important factor in intestinal inflammation.…”