Diet, nutraceuticals and the tear film

Jalbert, Isabelle

doi:10.1016/j.exer.2013.08.016

Cited by 35 publications

(33 citation statements)

References 92 publications

(152 reference statements)

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“…Both types of fatty acids are essential for lipid formation, but greater consumption of omega-3 may be beneficial (Jalbert, 2013). Omega-3 oils may reduce tear osmolarity, improve tear film stability, and reduce ocular redness by reducing inflammation (Deinema et al, 2017).…”

Section: Nutrition and Hydrationmentioning

confidence: 99%

“…Omega-3 oils may reduce tear osmolarity, improve tear film stability, and reduce ocular redness by reducing inflammation (Deinema et al, 2017). Lipids that are found on the ocular surface are derived from omega-3 fatty acids (Jalbert, 2013). Lipid mediators generated by omega-3 lipid stimulate macrophages to ingest apoptotic neutrophils and reduce the formation of fibroblasts, thus promoting a healthy ocular surface tissue (Barabino et al, 2017).…”

Section: Nutrition and Hydrationmentioning

confidence: 99%

“…The tear film is measured by osmolarity, volume, and stability (Jalbert, 2013). Osmolarity is the osmotic concentration of electrolytes of the ocular surface and is a biomarker for a healthy ocular surface.…”

mentioning

confidence: 99%

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Menopause and Dry Eye Syndrome

Lurati¹

2019

Nursing for Women's Health

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Section: Nutrition and Hydrationmentioning

confidence: 99%

Section: Nutrition and Hydrationmentioning

confidence: 99%

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Menopause and Dry Eye Syndrome

Lurati¹

2019

Nursing for Women's Health

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“…The ink is then transferred to the surface of the target substrates. While the ink is on the ridges of the pattern on the printing cylinder in flexography [87,94,95], gravure printing relies on impressing the film into the cavities of the roll where the ink resides ( Figure 4c) [113]. Both these two printing methods are intrinsically robust and can enable large-area manufacturing [113,[119][120][121][122][123][124].…”

Section: Temple and Non-template Fabrication Methodsmentioning

confidence: 99%

“…Electrolytes, metabolites, lipids, and proteins/peptides are widely available in the complex extracellular fluid of tears secreted from lacrimal glands, ocular surface epithelial cells, goblet cells, and blood [95]. Through electrochemical biosensor applications, these complex extracellular fluids can be measured for desirable health monitoring analyses [59,82,95,96]. As a natural choice, a contact lens can integrate an amperometric glucose sensor to analyze the tear.…”

Section: Tear Analysismentioning

confidence: 99%

Recent Developments of Flexible and Stretchable Electrochemical Biosensors

Yang

Cheng

2020

Micromachines

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The skyrocketing popularity of health monitoring has spurred increasing interest in wearable electrochemical biosensors. Compared with the traditionally rigid and bulky electrochemical biosensors, flexible and stretchable devices render a unique capability to conform to the complex, hierarchically textured surfaces of the human body. With a recognition element (e.g., enzymes, antibodies, nucleic acids, ions) to selectively react with the target analyte, wearable electrochemical biosensors can convert the types and concentrations of chemical changes in the body into electrical signals for easy readout. Initial exploration of wearable electrochemical biosensors integrates electrodes on textile and flexible thin-film substrate materials. A stretchable property is needed for the thin-film device to form an intimate contact with the textured skin surface and to deform with various natural skin motions. Thus, stretchable materials and structures have been exploited to ensure the effective function of a wearable electrochemical biosensor. In this mini-review, we summarize the recent development of flexible and stretchable electrochemical biosensors, including their principles, representative application scenarios (e.g., saliva, tear, sweat, and interstitial fluid), and materials and structures. While great strides have been made in the wearable electrochemical biosensors, challenges still exist, which represents a small fraction of opportunities for the future development of this burgeoning field.

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Wireless Non‐Invasive Monitoring of Cholesterol Using a Smart Contact Lens

et al. 2022

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Herein, a wireless and soft smart contact lens that enables real‐time quantitative recording of cholesterol in tear fluids for the monitoring of patients with hyperlipidemia using a smartphone is reported. This contact lens incorporates an electrochemical biosensor for the continuous detection of cholesterol concentrations, stretchable antenna, and integrated circuits for wireless communication, which makes a smartphone the only device required to operate this lens remotely without obstructing the wearer's vision. The hyperlipidemia rabbit model is utilized to confirm the correlation between cholesterol levels in tear fluid and blood and to confirm the feasibility of this smart contact lens for diagnostic application of cholesterol‐related diseases. Further in vivo tests with human subjects demonstrated its good biocompatibility, wearability, and reliability as a non‐invasive healthcare device.

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Diet, nutraceuticals and the tear film

Cited by 35 publications

References 92 publications

Menopause and Dry Eye Syndrome

Menopause and Dry Eye Syndrome

Recent Developments of Flexible and Stretchable Electrochemical Biosensors

Wireless Non‐Invasive Monitoring of Cholesterol Using a Smart Contact Lens

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