Diet in the Management of Hyperlipidemic Patients

Mancini, Mario; Farinaro, Eduardo; Moro, Christian; Marino, L.; Rubba, R.; Postiglione, Alfredo; Oriente, P

doi:10.1007/978-1-4684-3258-9_13

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Cholesterol-lowering Effect Lasts For Several Months In Free1

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1977

1982

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Cited by 3 publications

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“…It has also been shown that for lowering serum con centration of cholesterol, it should be reduced in the diet to less than 300 mg/day (4,33). Moreover, it has been recently reemphasized that fiber-rich foods may have a protective effect against atherosclerosis by lowering serum cholesterol.…”

Section: Cholesterol-lowering Effect Lasts For Several Months In Freementioning

confidence: 99%

Feedback Regulation of Metabolism by Dietary Constituents: Lipids

Mancini¹,

Postiglione²,

Marino³

1977

Ann Nutr Metab

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Cholesterol is distributed in different body pools. Input in these pools takes place through absorption of dietary cholesterol and endogenous synthesis. Absorption is limited in man. Endogenous synthesis is under negative feedback control, but its physiological relevance in man is less well established. Recent studies in familial hypercholesterolemia have shown a slower catabolism of low density hpoproteins (LDL) and an overproduction of apoprotein B. It seems that also the synthesis of the apoprotein B is controlled by a feedback mechanism. Overall concentration of lipids and hpoproteins in plasma is determined by the interaction between several genetic and dietary feedback mechanisms.

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Section: Cholesterol-lowering Effect Lasts For Several Months In Freementioning

confidence: 99%