Diet, faecal pH and colorectal cancer

Low-Calorie Bread Baked with Charred Cellulose Granules and Wheat Flour to Eliminate Toxic Xanthene Food Dye in the Alimentary Canal

“…Such circumambient conditions as the pH value, ionic strength, and food materials in the alimentary canal are more complex. It is possible not to adsorb xanthene food dyes to the charred cellulose granules under such conditions in the alimentary canal, so we examined whether the adsorption of the xanthene food dye (erythrosine) to the charred cellulose granules would occur at around pH 6.5, which is the fecal pH value in healthy people, [29][30][31][32][33][34][35][36][37] and under other conditions. pH dependence of the adsorption of erythrosine to charred cellulose granules It was necessary to know whether the adsorption of erythrosine to charred cellulose granules would occur or not at the same pH values as that in the alimentary canal, particularly at around pH 6.5 which is the fecal pH value for healthy people.…”

“…30,33) The fecal pH value in healthy people is therefore generally known to be around 6.5. [29][30][31][32][33][34][35][36][37] The pH dependence of the adsorption of erythrosine to charred cellulose granules was examined in a 10 mM Tris-HCl buffer at pH 6.0, 6.6, 6.7, 6.8, 6.9, and 7.0, the respevtive amounts of erythrosine adsorbed to the charred cellulose granules being 0.92, 0.88, 0.58, 0.14, 0.06, and 0.08 mg/g (Table 5). Although the adsorption of erythrosine was sharply decreased when the pH value approached 7.0, erythrosine was adsorbed to the charred cellulose granules at around pH 6.5.…”

“…The adsorption of erythrosine for 10 mM Tris-HCl at pH 6.00, 6.60, 6.70, 6.80, 6.90, and 7.00 was studied, a fecal pH value of 6.5 being general in healthy people. [29][30][31][32][33][34][35][36][37] The adsorption test was performed by column chromatography according to the method of Tabara et al…”

Self-assessment of faecal pH and faecal bulk in epidemiological studies

“…vegetarians (V) and non-vegetarians (NV). Dietary fibre has been shown to lower faecal pH and to increase faecal daily wet weight (van Dokkum et al, 1983).…”

Faecal pH, dietary fibre intake, and proneness to colon cancer in four South African populations

“…Currently, there is considerable interest in faecal pH value in relation to proneness to colon cancer, especially as regulated by fibre intake (Thornton, 1981;van Dokkum et al, 1983;Jacobson et al, 1984;Samuelson et al, 1985). In South Africa, mean faecal pH values of groups (numbering 30 boys, 30 girls) of rural and urban black schoolchildren aged 10-12 years were found to be 6.13 and 6.25, values significantly lower (P<0.01) than that of white schoolchildren, 6.88 (Walker et al, 1979).…”