“…Other studies have focused on gene expression in response to various diets or drugs, measuring the effects of a high-fat diet and obesity-related hypertension on gene expression of cardiac tissues 74,75 and the acute phase response to pharmaceuticals. 76 Our laboratory is currently investigating the effects of age and diet on gene expression in the liver, b,c colon, 77 skeletal muscles, 78 cerebral cortex, 79 and adipose tissues of dogs. Given the current incidence of obesity in dogs, studies reported by Philip-Couderc et al 74,75 are of particular interest.…”