Diet and physical activity in the association between depression and metabolic syndrome: Constances study

Matta, Joane; Hoertel, Nicolas; Kesse‐Guyot, Emmanuelle; Plesz, Marie; Wiernik, Emmanuel; Carette, Claire; Czernichow, Sébastien; Limosin, Frédéric; Goldberg, Marcel; Zins, Marie; Lemogne, Cédric

doi:10.1016/j.jad.2018.09.072

Cited by 48 publications

(30 citation statements)

References 45 publications

(47 reference statements)

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“…Respondents were asked to indicate on a scale from 0 (rarely or none of the time) to 3 (most of the time) how often they experience 20 symptoms related to depression (e.g., I felt everything I did was an effort). This questionnaire has been designed for use in community studies (Airagnes et al, 2016b;Matta et al, 2019;Radloff, 1977;Roy, 1981) and validated in adult samples of all ages with psychiatric disorders (Irwin et al, 1999;Shafer, 2006), including adults with schizophrenia spectrum disorder (Herniman et al, 2017). In our study, internal consistency reliability of the CES-D scale was acceptable, with Cronbach's alpha=0.72.…”

Section: Assessment Of Subsyndromal and Syndromal Depressive Symptomsmentioning

confidence: 52%

Subsyndromal and syndromal depressive symptoms among older adults with schizophrenia spectrum disorder: Prevalence and associated factors in a multicenter study

Hoertel¹,

Jaffré²,

Raykeer³

et al. 2019

Journal of Affective Disorders

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Background: Few studies have examined the prevalence and correlates of subsyndromal and syndromal depressive symptoms (SSSD) among older adults with schizophrenia spectrum disorder. In this report, we examined the prevalence of SSSD and their associations with sociodemographic characteristics, clinical characteristics of schizophrenia, comorbidity, psychotropic medications, quality of life, functioning and mental health care utilization in a large, multicenter sample of older adults with schizophrenia spectrum disorder. Methods: Data from the Cohort of individuals with Schizophrenia Aged 55 years or more (CSA) were used to examine the prevalence of SSSD, defined using the Center of Epidemiologic Studies Depression (CESD) scale. Clinical characteristics associated with SSSD were explored. Results: Among 343 older adults with schizophrenia spectrum disorder, 78.1% had either subsyndromal (30.6%) or syndromal (47.5%) depressive symptoms. SSSD were independently associated with positive and negative symptoms, lower quality of life, non-late-onset psychosis, benzodiazepine use and urbanicity. There were no significant associations of SSSD with other sociodemographic characteristics and psychotropic medications, or with general medical conditions. We found no significant differences in the proportion of participants who were treated with antidepressants between those with syndromal depressive symptoms and those without depression (22.1% vs. 20.0%, p = 0.89). SSSD were not associated with higher mental health care utilization. Limitations: Data were cross-sectional and depression was not evaluated with a semi-structured interview. Conclusion: SSSD may be highly prevalent and under-assessed and/or undertreated among older adults with schizophrenia spectrum disorder. Our findings should alert clinicians about the need to assess systematically and regularly depression in this vulnerable population.

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Section: Assessment Of Subsyndromal and Syndromal Depressive Symptomsmentioning

confidence: 52%

Subsyndromal and syndromal depressive symptoms among older adults with schizophrenia spectrum disorder: Prevalence and associated factors in a multicenter study

Hoertel¹,

Jaffré²,

Raykeer³

et al. 2019

Journal of Affective Disorders

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“…Each of the three items was noted 0 if the answer was no; 1 if practice was regular but low (less than 15 minutes for sports, or 2 hours for the other two weekly); 2 if practice was regular and higher. Data regarding the score obtained by summing the three items has been published [49]. People with a score below three were considered at risk of low physical activity.…”

Section: Outcome Variables: Co-occurring Behavioral Risk Factorsmentioning

confidence: 99%

Association between unemployment and the co-occurrence and clustering of common risky health behaviors: Findings from the Constances cohort

et al. 2020

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Background Unemployment is associated with a high prevalence of risky health behaviors. Mortality increases with the number of co-occurring risky behaviors but whether these behaviors cooccur with a greater than expected frequency (clustering) among unemployed people is not known. Methods Differences according to unemployment status in co-occurrence and clustering of smoking, alcohol abuse, low leisure-time physical activity and unhealthy diet (marked by low fruit and vegetable intake) were assessed in 65,630 salaried workers, aged 18 to 65, who were participants in Constances, a French population-based cohort. Among them, 4573 (7.0%) were unemployed without (n = 3160, 4.8%) or with (n = 1413, 2.1%) past experience of unemployment. Results Compared to the employed, unemployed participants without or with past experience of unemployment were similarly overexposed to each risky behavior (sex and age adjusted odds-ratios ranging from 1.38 to 2.19) except for low physical activity, resulting in higher rates of co-occurrence of two, three and four behaviors (relative risk ratios, RRR 1.20 to 3.74). Association between behavior co-occurrence and unemployment did not vary across gender, partnership status or income category. Risky behavior clustering, i.e., higher than expected co-occurrence rates based on the prevalence of each behavior, was similar across unemployment status. The same observations can be made in employed participants with past experience of unemployment, although overexposure to risky behaviors (ORs 1.15 to

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“…Associations between various types of diet and the pathology of depression have been discovered in the last two decades [5,6,7,8]. For instance, evidence has emerged that the Mediterranean-style diet has beneficial effects on neurological disorders, including stroke, depression, and cognitive impairment [9,10].…”

Section: Introductionmentioning

confidence: 99%

Fish Oil, but Not Olive Oil, Ameliorates Depressive-Like Behavior and Gut Microbiota Dysbiosis in Rats under Chronic Mild Stress

Tung

Lin

et al. 2019

Biomolecules

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Background: This study investigated the effects of fish oil and olive oil in improving dysbiosis and depressive-like symptoms. Methods and results: Male rats were fed normal, fish oil-rich or olive oil-rich diets for 14 weeks. Chronic mild stress (CMS) was administered from week 2. The sucrose preference test (SPT) and forced swimming test (FST) were used to determine depressive-like behavior. The SPT results revealed that the CMS, CMS with imipramine (CMS+P) treatment, and CMS with olive oil diet (CMS+O) groups exhibited significantly reduced sucrose intake from week 8, whereas the fish oil diet (CMS+F) group exhibited significantly reduced sucrose intake from week 10. The FST results showed that the immobile time of the CMS+F group was significantly less than that of the CMS-only group. Next generation sequencing (NGS) results showed CMS significantly reduced the abundance of Lactobacillus and increased that of Marvinbryantia and Ruminiclostridium_6. However, the CMS+F group showed an increase in the abundance of Eisenbergiella, Ruminococcaceae_UCG_009, and Holdemania, whereas the CMS+O group showed an increase in the abundance of Akkermansia. Conclusions: CMS stimuli altered the gut microbiome in depressed rats. Fish oil and olive oil exerted part of a prebiotic-like effect to ameliorate dysbiosis induced by CMS. However, only fish oil ameliorated depressive-like symptoms.

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Diet and physical activity in the association between depression and metabolic syndrome: Constances study

Cited by 48 publications

References 45 publications

Subsyndromal and syndromal depressive symptoms among older adults with schizophrenia spectrum disorder: Prevalence and associated factors in a multicenter study

Subsyndromal and syndromal depressive symptoms among older adults with schizophrenia spectrum disorder: Prevalence and associated factors in a multicenter study

Association between unemployment and the co-occurrence and clustering of common risky health behaviors: Findings from the Constances cohort

Fish Oil, but Not Olive Oil, Ameliorates Depressive-Like Behavior and Gut Microbiota Dysbiosis in Rats under Chronic Mild Stress

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