“…Whether the latter data reflect the maximum BMI before disease onset is unknown, and the relationship between AP and CP according to the ‘necrosis-fibrosis’ hypothesis [1,2,3,22,23] was not taken into account. Therefore, data in the current literature supporting a link between diet and overweight as potential risk factor for ACP are either conflicting [23,24,25,26,27,28,29,30,31] or weak [26,38]. In contrast, we provide first clinical evidence (prospective study) indicating that obesity (due to hypercaloric nutrition) is probably a predisposing risk factor for ACP.…”