Diet and asthma

Han, Yueh‐Ying; Forno, Erick; Holguín, Fernando; Celedón, Juan C.

doi:10.1097/aci.0000000000000179

Cited by 40 publications

(41 citation statements)

References 51 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Temporal changes in dietary patterns and obesity may partly explain the asthma epidemic in industrialized countries . Whereas a Western diet (rich in proinflammatory foods and poor in antioxidant foods) has been linked to asthma incidence and prevalence, an “anti‐inflammatory diet” has been associated with decreased asthma symptoms .…”

Section: Discussionmentioning

confidence: 99%

Health risk behaviors, violence exposure, and current asthma among adolescents in the United States

Han

Forno

Celedón

2019

Pediatric Pulmonology

Self Cite

View full text Add to dashboard Cite

Background Asthma may worsen during adolescence, due to both health risk behaviors and psychosocial stressors commonly encountered during this life stage. Methods Cross‐sectional study of 24 612 high school students who participated in the 2009 and 2011 National Youth Risk Behavior Survey. Multivariable logistic regression was used to examine the relation between self‐reported health risk behaviors or psychosocial stressors and current asthma. Mediation analysis was performed to assess whether depressive symptoms or suicidal behavior contribute to the link between psychosocial stressors and asthma. Results Current asthma was reported by 13.1% of the study participants. In a multivariable analysis, female sex, obesity, shorter sleep duration, frequent soda/pop consumption, and marijuana use were each significantly associated with 14‐36% increased odds of asthma. Any violent behavior (adjusted odds ratio [OR] = 1.12, 95% confidence interval [CI] = 1.02‐1.24), any victimization (OR = 1.43, 95%CI = 1.29–1.58), any suicidal behavior (OR = 1.41, 95%CI = 1.22‐1.64) and having felt sad or hopeless in the past year (OR = 1.57, 95%CI = 1.40‐1.75) were each associated with current asthma. In a mediation analyses, having felt sad/hopeless and suicidal behaviors accounted for 21% and 14%, respectively, of the victimization‐asthma association. Conclusion Potentially modifiable risk factors, including obesity, short sleep duration, frequent soda/pop consumption, and psychosocial stressors are associated with asthma in US adolescents. Promoting healthier lifestyles, as well as screening for violence exposure and treating depressive symptoms, could help reduce asthma burden in this population.

show abstract

Section: Discussionmentioning

confidence: 99%

Health risk behaviors, violence exposure, and current asthma among adolescents in the United States

Han

Forno

Celedón

2019

Pediatric Pulmonology

Self Cite

View full text Add to dashboard Cite

show abstract

“…Airway and systemic inflammation as well as oxidative stress are recognized mechanisms involved in the pathogenesis of asthma and allergic diseases . Antioxidants reduce reactive oxygen species (ROS) and epidemiological studies have reported inverse associations between diets rich in antioxidants and allergic diseases; however, results are inconsistent and previous studies on school age intake have often been cross‐sectional .…”

Section: Introductionmentioning

confidence: 99%

Dietary total antioxidant capacity in early school age and subsequent allergic disease

Gref

Rautiainen

Gruzieva

et al. 2017

Clin Experimental Allergy

View full text Add to dashboard Cite

SummaryBackgroundDietary antioxidant intake has been hypothesized to influence the development of allergic diseases; however, few prospective studies have investigated this association.ObjectiveOur aim was to study the association between total antioxidant capacity (TAC) of the diet at age 8 years and the subsequent development of asthma, rhinitis and sensitization to inhalant allergens between 8 and 16 years, and to assess potential effect modification by known risk factors.MethodsA total of 2359 children from the Swedish birth cohort BAMSE were included. Dietary TAC at age 8 years was estimated by combining information on the child's diet the past 12 months from a food frequency questionnaire with a database of common foods analysed with the oxygen radical absorbance capacity method. Classification of asthma and rhinitis was based on questionnaires, and serum IgE antibodies were measured at 8 and 16 years.ResultsA statistically significant inverse association was observed between TAC of the diet and incident sensitization to inhalant allergens (adjusted odds ratio: 0.73, 95% confidence interval: 0.55–0.97 for the third compared to the first tertile, P‐value for trend = 0.031). Effect modification by traffic‐related air pollution exposure was observed, with a stronger association between dietary TAC and sensitization among children with low traffic‐related air pollution exposure (P‐value for interaction = 0.029). There was no evidence for effect modification by GSTP1 or TNF genotypes, although these results should be interpreted with caution. No clear associations were observed between TAC and development of rhinitis or asthma, although a significant inverse association was observed for allergic asthma (OR adj 0.57, 95% CI 0.34–0.94).Conclusions and Clinical RelevanceHigher TAC of the diet in early school age may decrease the risk of developing sensitization to inhalant allergens from childhood to adolescence. These findings indicate that implementing an antioxidant‐rich diet in childhood may contribute to the prevention of allergic disease.

show abstract

“…A variety of antioxidant supplements and nutrients has been studied for the treatment of asthma. 16,47 A few studies have shown the beneficial effect of antioxidants on pulmonary functions and on asthmatic symptoms. 17,18 In our study, we studied the relationships between oxida-tive stress markers and either vitamins in serum or the daily intake of vitamins over a very short period, and no relationships were found.…”

Section: Discussionmentioning

confidence: 99%

Relationship between Oxidative Stress, Physical Activity, and Vitamin Intake in Patients with Asthma

et al. 2017

View full text Add to dashboard Cite

Background Oxidative stress plays an important role in the pathogenesis of bronchial asthma. Antioxidant nutrition and supplementation have been used to reduce oxidative stress. However, a clinical trial with antioxidant supplementation showed no beneficial effects in patients with asthma. On the other hand, physical activity is related to the prognosis of chronic obstructive pulmonary disease (COPD) and is also related to oxidant status. We investigated the relationships between oxidative stress, serum levels of vitamins, dietary vitamin intake, daily activities, and pulmonary functions in patients with asthma. Methods Eighteen patients with bronchial asthma were enrolled in this study. Reactive oxidative stress was assessed by measuring organic hydroperoxides (diacron reactive oxygen metabolites: dROM) in sera and by measuring H 2 O 2 levels in exhaled breath condensates. The biological antioxidant capacity in serum was evaluated by measuring antioxidant potential capacity against ferric ion. We also assessed pulmonary functions, fraction of exhaled nitric oxide, serum levels of vitamins, dietary vitamin intake, and physical activities. Results There were no relationships between the index of oxidative stress (dROM and H 2 O 2 in exhaled breathe condensates) and pulmonary functions, serum levels of vitamins, daily vitamin intakes, and activity levels in patients with asthma. Conclusion The status of transient oxidative stress may not be related to daily activities, vitamin levels, and pulmonary functions in patients with asthma in a real-life setting. However, our results were obtained in the short-term period from a small number of subjects, so a large longitudinal study is required to ascertain the relationships between oxidative stress, physical activity and vitamin intake in patients with asthma.

show abstract

Diet and asthma

Cited by 40 publications

References 51 publications

Health risk behaviors, violence exposure, and current asthma among adolescents in the United States

Health risk behaviors, violence exposure, and current asthma among adolescents in the United States

Dietary total antioxidant capacity in early school age and subsequent allergic disease

Relationship between Oxidative Stress, Physical Activity, and Vitamin Intake in Patients with Asthma

Contact Info

Product

Resources

About