Dielectric Properties of Normal and Abnormal Lipoproteins in Aqueous Solution

Essex, C G; Grant, E H; Sheppard, R J; South, G. P.; Symonds, M. S.; Mills, G.L.; Slack, Joan

doi:10.1111/j.1749-6632.1977.tb55927.x

Cited by 24 publications

(15 citation statements)

References 29 publications

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“…Measurements of = E' -jc" were made at a temperature of 10 "C at 15 frequencies in the range 2-18 GHz and at a concentration of 109 mg/ml. Although extensive dielectric work has been performed at lower frequencies on aqueous solutions of LDL [Essex et al, 1977b;Chana et al, 19801, the present work is the first to be carried out in the dispersion region of the water. A temperature of 10°C was chosen in order to span as large a section as possible of the water dispersion.…”

Section: Dielectric Behavior Of Human Serum Low-density Lipoprotein (mentioning

confidence: 99%

Dielectric behavior of water in biological solutions: Studies on myoglobin, human low‐density lipoprotein, and polyvinylpyrrolidone

Grant

McClean

Nightingale

et al. 1986

Bioelectromagnetics

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The dielectric behavior of the aqueous solutions of three widely differing macromolecules has been investigated: myoglobin, polyvinylpyrrolidone (PVP), and human serum low-density lipoprotein (LDL). It was not possible to interpret unambiguously the dielectric properties of the PVP solution in terms of water structure. The best interpretation of the dielectric data on the myoglobin and LDL solutions was that, in both cases, the macromolecule attracts a layer of water of hydration one or two water molecules in width. For LDL, this corresponds to a hydration factor of only 0.05 g/g, whereas for myoglobin the figure is nearer 0.6 g/g. With myoglobin, part of the water of hydration exhibits its dispersion at frequencies of a few GHz, and the rest disperses at lower frequencies, perhaps as low as 10-12 MHz. The approximate constancy of the width of the hydration shell for two molecules as dissimilar in size as LDL and myoglobin confirms that the proportion of water existing as water of hydration in a biological solution depends critically on the size of the macromolecules as well as on their concentration.

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Section: Dielectric Behavior Of Human Serum Low-density Lipoprotein (mentioning

confidence: 99%

Dielectric behavior of water in biological solutions: Studies on myoglobin, human low‐density lipoprotein, and polyvinylpyrrolidone

Grant

McClean

Nightingale

et al. 1986

Bioelectromagnetics

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“…Biogenic synthesis of AgNPs was done by using fruit of Choreospondias axillaris extract (Essex et al, 1997). Fruits were thoroughly washed in deionized water, outer seed covering of the fruit was peeled off and the fleshy part was taken out , 10 gm of this flashy part was added in 100ml of deionized water, boiled for 30 minutes, and filtered through Whattmann no.…”

Section: Synthesis Of Silver Nanoparticles Agnpsmentioning

confidence: 99%

“…The dielectric behavior of biological tissue depends upon the properties of the molecules comprising, their size, shape and the polarizability and other factors like surface charges, bound water, hydration water and other factors (Essex et al, 1997). Enhancement of antibacterial activities of antibiotics in combination with AgNPs against different strains of Research Article bacteria have already been reported by many researchers (Dhas et al, 2013).…”

Section: Introductionmentioning

confidence: 97%

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Biophysical and Characterizations of Silver Nanoparticles used as Salmonella typhi Detector

Ahmed

2014

Int J Appl Sci Biotechnol

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The present study mainly focuses of combined action of Nepali hog plum as well as citrate synthesized silver nanoparticles (AgNPs) and Amikacin, as an antibiotic. The synergistic actions of citrate stabilized silver nanoparticles (AgNPs with chem) were compared with that of Nepali hog plum Choerospondia saxillaris (Lapsi) synthesized silver nanoparticles (AgNPs with plant), together with action of antibiotic on selected bacterial strains of Salmonella typhi.The synthesized AgNPs were characterized through UV-Vis spectroscopy, Transmission electron microscopy and X-ray diffraction technique. The size of the synthesized silver nanoparticles was measured by Transmission Electron Microscope (TEM) and X-ray diffraction (XRD).

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“…Application of dielectric techniques to the study of native and trypsin-treated LDL may provide information on the nature of the surface charge resulting from trypsin treatment. Dieletric studies may also be used to reveal whether any changes in the internal organization occur [2].…”

mentioning

confidence: 99%

A comparative dielectric study of human serum low density lipoprotein before and after partial digestion by trypsin

Chana¹,

Chapman²,

Sheppard³

et al. 1980

J Supramol Struct

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The relative permittivity of aqueous solutions of human serum low density lipoprotein (LDL) and partially trypsin digested lipoprotein (T-LDL) has been determined for various concentrations at 20 degrees C over the frequency range 0.15-100 MHz. Comparison of the dielectric dispersion curves for the digested lipoprotein with those for the native preparation revealed a larger low-frequency dielectric increment, which may be attributed to an increase in the number of counterions moving over the surface of the molecule. An explanation of this observation is an elevation of 70% in the net negative charge on the surface of the trypsin-treated particle as compared to its native counterpart.

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Dielectric Properties of Normal and Abnormal Lipoproteins in Aqueous Solution

Cited by 24 publications

References 29 publications

Dielectric behavior of water in biological solutions: Studies on myoglobin, human low‐density lipoprotein, and polyvinylpyrrolidone

Dielectric behavior of water in biological solutions: Studies on myoglobin, human low‐density lipoprotein, and polyvinylpyrrolidone

Biophysical and Characterizations of Silver Nanoparticles used as Salmonella typhi Detector

A comparative dielectric study of human serum low density lipoprotein before and after partial digestion by trypsin

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