Perfluoroisobutyronitrile (C 4 F 7 N) has received extensive attention over the past three years as an environmental friendly gas insulating medium. At present, there are few studies on the compatibility of C 4 F 7 N with metal materials used in the electrical equipment. In this paper, we constructed a gas-solid interfacial reaction platform and carried out aging tests for C 4 F 7 N-CO 2 gas mixture at different temperatures. The composition of the gas mixture and the surface morphology and the elemental composition of copper, aluminum were explored. The interaction mechanism between C 4 F 7 N-CO 2 gas mixture and metal surface was also analyzed. It was found that C 4 F 7 N-CO 2 gas mixture has better compatibility with aluminum than copper. The reaction between C 4 F 7 N-CO 2 gas mixture and heated copper at 220 • C produces the gaseous by-product C 3 F 6. The surface color of copper deepens and the corrosive degree increases with temperature, while the interaction between C 4 F 7 N and heated aluminum does not cause gas decomposition and metal corrosion. In general, the thermal stability of C 4 F 7 N-CO 2 gas mixture associated with heated copper and aluminum is inferior to that of SF 6. INDEX TERMS C 4 F 7 N-CO 2 , thermal compatibility, copper, aluminum, SF 6 alternative gas.