Die Wirkung von Dihydrotachysterin (AT10) auf H�hner

Metastatic Calcification Induced by Hytakerol in Chickens Infected With Plasmodium gallinaceum

“…The response of uninfected chicks to the hytakerol treatment was comparable to that observed previously in other vertebrate species (Mercado and von Brand, 1962;Hass et al, 1958;Holtz and Tilgner-Peter, 1957;von Brand and Holtz, 1933;and von Brand and Holtz, 1929). In general, an increase in the incidence of calcification as well as an increase in the amounts of calcium deposited occurred.…”

“…No calcifications were observed in the kidney, stomach, and lung of adult hens studied by Holtz and Tilgner-Peter (1957) and in a study with adult canaries (von Brand and Holtz, 1933) only two specimens out of a total of thirty showed spontaneous calcifications and these were confined to the kidney. No calcifications were observed in the kidney, stomach, and lung of adult hens studied by Holtz and Tilgner-Peter (1957) and in a study with adult canaries (von Brand and Holtz, 1933) only two specimens out of a total of thirty showed spontaneous calcifications and these were confined to the kidney.…”

“…(3) sex and age of the host; Holtz and Tilgner-Peter (1957) treated infantile female and male birds and adult hens with 5,000 toxic doses of dihydrotachysterol (AT 10) and found female birds to be less susceptible than males and infantile ones less than the adult. (2) host species; it is well established that different species react differently to irradiated ergosterol derivatives; the present study and our previous rat study, in which the same hytakerol concentrate was used, emphasize this point.…”