Die Vorhersagefaktoren einer erfolgreichen selektiven Lasertrabekuloplastik bei Offenwinkelglaukom

Gračner, Tomaž; Naji, Mateja; Hudovernik, Mojca; Gracner, B; Pahor, Dušica

doi:10.1055/s-2007-963744

Cited by 15 publications

(11 citation statements)

References 10 publications

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“…The present study aims to answer the question of factors that can predict success of SLT over a longer period of time (4 years). Predictive factors have been reported by Gracner et al6 showing a negative correlation between successful SLT and the grade of trabecular meshwork pigmentation and diabetes. The authors did not find any significant correlations between successful SLT and baseline IOP, age, sex, hypertension, family history of glaucoma, previous anterior segment surgery, laser energy used and local antiglaucoma therapy.…”

Section: Discussionmentioning

confidence: 80%

“…Comparisons among studies are always difficult to perform due to different populations studied, different time periods, how failure was defined, etc. The fact that Gracner et al6 did not find a significant correlation between baseline IOP and success might be due to different levels of IOP in the patients included. In our study the mean level of baseline IOP was 24.7 mmHg meanwhile Gracner et al6 included patients with IOP 22.5 mmHg.…”

Section: Discussionmentioning

confidence: 86%

“…The fact that Gracner et al6 did not find a significant correlation between baseline IOP and success might be due to different levels of IOP in the patients included. In our study the mean level of baseline IOP was 24.7 mmHg meanwhile Gracner et al6 included patients with IOP 22.5 mmHg. Mao et al8 found a positive correlation between IOP reduction and IOP before SLT treatment including patients with a baseline IOP of 26 mm Hg.…”

Section: Discussionmentioning

confidence: 86%

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Predictive factors of success in selective laser trabeculoplasty (SLT) treatment

Ayala¹,

Chen²

2011

OPTH

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Purpose:Glaucoma is a progressive optic neuropathy that may lead to blindness. Reducing intraocular pressure (IOP) is the only known treatment to slow progression in glaucoma. IOP can be reduced by pharmaceutical treatment, laser and surgery. The aim of the present study was to assess predictive factors of success after selective laser trabeculoplasty (SLT) treatment.Methods:We used a retrospective chart review of eyes that underwent SLT between January 1, 2005 and December 31, 2005. The dependent variable was time to failure after SLT treatment. Failure after SLT was defined as any changes in the medical treatment, and/or a new SLT treatment was performed and/or the patient was sent for surgery. All patients were treated with 90° SLT. A multivariate regression analysis was performed to assess correlation between time to failure after SLT and age, gender, IOP before treatment, number of medications used, SLT number, amount of spots, laser energy used, grade of angle, pigmentation and diagnosis.Results:120 eyes of 120 patients were identified. The average time to failure after SLT was 18 months. The predictive factors identified were: age, IOP before SLT and dose.Conclusion:Predictive factors identified in our study were high baseline IOP, age and amount of laser energy used. Our study confirms previous results about baseline IOP as a predictive factor.

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Section: Discussionmentioning

confidence: 80%

Section: Discussionmentioning

confidence: 86%

Section: Discussionmentioning

confidence: 86%

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Predictive factors of success in selective laser trabeculoplasty (SLT) treatment

Ayala¹,

Chen²

2011

OPTH

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“…Johnson et al showed that the 2-week visit post-SLT predicted the 4-week and 3-month visits in the same eye if the 2-week visit demonstrated a decrease in IOP 20. Different studies showed the predictive value of the baseline IOP as a predictor of success following SLT 21–22. It was shown that SLT not only lowers the IOP in the treated eye, but also has a short-term IOP-lowering effect in the untreated eye 23…”

Section: Discussionmentioning

confidence: 99%

Effect of prior cataract surgery on the long-term outcome of selective laser trabeculoplasty

Shazly¹,

Latina²,

Dagianis³

et al. 2011

OPTH

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Objective:To determine if pseudophakia affects selective laser trabeculoplasty (SLT) intraocular pressure (IOP) lowering effect.Methods:A retrospective chart review was performed on 94 eyes of 75 consecutive patients who underwent SLT as primary treatment for ocular hypertension and primary open-angle glaucoma between 2002 and 2005 and completed at least 30 months follow up. Patients were excluded if they required additional glaucoma medications, laser, or ocular surgery during the follow-up period. Patients were categorized as phakics or pseudophakics. Independent-samples t-test was performed to compare the mean percentage of IOP reduction at 3, 6, 12, 18, and 30 months after SLT between the phakic and pseudophakic groups.Results:Seventy-six phakic and 18 pseudophakic eyes were included. IOP reduction in phakic group was 27.4% (2 week), 29.8% (3 months), 27.7% (9 months), 27.4% at (12 months) and 27.3% at (30 months). In pseudophakic patients, the mean IOP reduction was 19.8% (2 weeks), 26.5% (3 months), 23.2% (9 months), 22.5% (12 months), and 25.9% (30 months). An independent-sample t-test compared the percentage of IOP reduction between the phakic and pseudophakic groups and revealed higher percentage of IOP reduction in the phakic group at 2 weeks by 7.6% (P = 0.01). P value for difference was 0.34 (3 months), 0.25 (6 months), 0.18 (9 months), 0.12 (12 months), 0.36 (18 months), and 0.7 (30 months) after SLT.Conclusions:SLT response was delayed in pseudophakic compared to phakic patients, while the long-term effectiveness of SLT is the same in both groups.

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“…Gracner et al 37 reported a negative correlation between successful SLT and the grade of TM pigmentation and diabetes. They did not find any significant correlations between successful SLT and baseline IOP, age, gender, hypertension, family history of glaucoma, previous anterior segment surgery, laser energy used or local antiglaucoma therapy.…”

Section: Mechanism Of Action Of Sltmentioning

confidence: 99%

Selective Laser Trabeculoplasty: An Overview

Jha

Bhartiya²,

Sharma

et al. 2012

Journal of Current Glaucoma Practice

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Given the obvious quality of life concerns with medical and surgical lowering of intraocular pressure (IOP), lasers have received considerable attention as a therapeutic modality for glaucoma.Selective laser trabeculoplasty (SLT) is increasingly being used in clinical practice as both the primary procedure and as an adjunct to medical and surgical therapy. Preliminary published evidence suggests that SLT is an effective, compliance-free, repeatable and safe therapeutic modality having only minor, transient, self-limiting or easily controlled side effects with no sequelae.This review attempts a broad overview of the current knowledge of its mechanism, efficacy, indications and limitations, point out the knowledge lacunae that still exist with respect to this highly promising technology which has captured the attention of glaucoma surgeons all over the world.How to cite this articleJha B, Bhartiya S, Sharma R, Arora T, Dada T. Selective Laser Trabeculoplasty: An Overview. J Current Glau Prac 2012;6(2):79-90.

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Die Vorhersagefaktoren einer erfolgreichen selektiven Lasertrabekuloplastik bei Offenwinkelglaukom

Abstract: SLT success in OAG with a mean follow-up time of 43.4 months was significantly predicted by the lower grade of trabecular meshwork pigmentation and the absence of diabetes mellitus.

Cited by 15 publications

References 10 publications

Predictive factors of success in selective laser trabeculoplasty (SLT) treatment

Predictive factors of success in selective laser trabeculoplasty (SLT) treatment

Effect of prior cataract surgery on the long-term outcome of selective laser trabeculoplasty

Selective Laser Trabeculoplasty: An Overview

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