Die verschiedenen Arten des gesetzm�ssigen Zellwachstums und ihre Beziehung zu Zellfunktion, Umwelt, Krankheit, maligner Geschwulstbildung und innerem Bauplan

Jacobj, Walther

doi:10.1007/bf00596491

Cited by 71 publications

(3 citation statements)

References 77 publications

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“…There are two main conditions which make the dNF possible: volume increase of the nucleus and alteration of the metabolic relations in dependence on the cell position (Jacobj 1942). In our investigations the dNF was also observed on nuclei with increased volumes (Fig.…”

Section: Discussionsupporting

confidence: 71%

Effect of 2,4-dichlorophenoxyacetic acid on nuclear division in stem segments ofPisum sativum L. cultivatedin vitro

Gantchev¹,

Bleiss²

1994

Biol. plant.

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We have investigated the influence of 2,4-dichlorophenoxyacetic acid (2,4-D) on the appearance of nuclear fragments, caused by direct nuclear division, as well as on mitotic activity in cultivated internodial stem segments of Pisum sativum L., cv. BOrdi, during 180 d of cultivation. Direct nuclear fragmentation (dNF) was indicated by the shape and structure of the nucleus as well as by the occurrence of 1C-and 3C-values of DNA, investigated cytophotometrically. The dNF occurred during the whole cultivation period in segments treated by 2,4-D in concentrations from 4 to 32 mg 1-1. In the presence of 2 mg 1 -t of 2,4-D .the dNF existed in the explants only up to 90 d. Mitotic activity was not observed in the 2,4-D-free control but occurred during the whole cultivation period when 2,4-D was added in concentrations from 2 to 16 mg 1-1. In the presence of 32 mg 1 -l of 2,4-D the level of mitotic activity was very low at the beginning and ceased after 60 d in culture.

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Section: Discussionsupporting

confidence: 71%

Effect of 2,4-dichlorophenoxyacetic acid on nuclear division in stem segments ofPisum sativum L. cultivatedin vitro

Gantchev¹,

Bleiss²

1994

Biol. plant.

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“…Although polyploid nuclei vary in size, it is generally felt that an increase in ploidy may result in a larger nucleus (Brodsky and Uryvaeva, 1985). Another reason for such an increase is that nuclear size may be determined by the functional state of the cell (Jacobj, 1942).…”

Section: Discussionmentioning

confidence: 98%

Changes in binucleation and cellular dimensions of rat left atrial myocytes after induced left ventricular infarction

Oberpriller

Aafedt

1987

Am. J. Anat.

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The left atrium of young rats has previously been demonstrated to respond with DNA synthesis and binucleation 11 days after left ventricular infarction. This investigation was designed to examine the hypertrophic response of the left atrial myocyte of the rat at 20 and 60 days after ventricular infarction. Male Sprague-Dawley rats were subjected to left coronary artery ligation (CAL) or sham operation. Following enzymatic separation, left atrial myocytes were examined at 20 and 60 days postoperation for number of nuclei and cellular dimensions (cell length, width and area, and nuclear area). Results demonstrated that the level of binucleation at 20 days (77.3%) and 60 days (71.3%) was nearly twice that observed in sham-operated animals, which were 33.1% binucleated at 20 days and 43.5% binucleated at 60 days. In both mononucleated and binucleated myocytes, the mean lengths, widths, and cell areas from CAL hearts were significantly greater than those of corresponding sham-operated animals. In all cases, these values were larger in binucleated myocytes than in mononucleated cells. The mean area of CAL cells was approximately twice that of sham-operated myocytes. With regard to mean lengths and widths, although both were greater in the CAL animals, there was a decrease in length and increase in width between 20 and 60 days in the CAL group. Mean nuclear areas were significantly greater in CAL myocytes than in those from the sham-operated group. These increases in nuclear number and cellular dimensions of the atrial myocyte are prominent features of the response to the stress imposed by left ventricular infarction.

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“…On n'a pas tenu compte séparé ment des noyaux des parties centrales et périphériques du lobule hépatique (cf. Jacobj [1942] Ce com portem ent est dû à la présence de classes nucléaires supérieu res (Jacobj [1942] La méthode de déterm ination de cette différence a été exposée en détail par Bûcher et Gattiker [1952] ; il est donc inutile d'y revenir ici. Ce qui, dans le présent travail, a posé un problèm e provient de ce que les distributions ne correspondent pas à des courbes normales, alors que le procédé m entionné plus haut ne peut s'appliquer qu'à ce type de courbes.…”

Section: Introductionunclassified

Le cycle diurne hépatique (Etude de la taille nucléaire et du caryogramme)

Suppan¹

1966

Cells Tissues Organs

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Die verschiedenen Arten des gesetzm�ssigen Zellwachstums und ihre Beziehung zu Zellfunktion, Umwelt, Krankheit, maligner Geschwulstbildung und innerem Bauplan

Cited by 71 publications

References 77 publications

Effect of 2,4-dichlorophenoxyacetic acid on nuclear division in stem segments ofPisum sativum L. cultivatedin vitro

Effect of 2,4-dichlorophenoxyacetic acid on nuclear division in stem segments ofPisum sativum L. cultivatedin vitro

Changes in binucleation and cellular dimensions of rat left atrial myocytes after induced left ventricular infarction

Le cycle diurne hépatique (Etude de la taille nucléaire et du caryogramme)

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