Die tuberöse Hirnsklerose

The Neuropathology of a Peculiar Form of Cerebro-Renal Syndrome in a Child

“…Multinucleate neuroblastic elements may be found in certain nerve tumours or in so-called gangliocytoma dysplasticum of the cerebellum (CHRISTENSEN 1937). However, they have an altogether different appearance -an abundant intensely eosinophiliccytoplasm (RUSSELL and RUBINSTEIN 1971) and stain in a similar way to the multinucleate glial cells found in tuberous sclerosis (HALLERVORDEN and KRUCKE 1956). The bi-and multinucleate cells found next to the uninucleate cells in our patient had a clear balloon cytoplasm.…”

Tuberous Sclerosis in a Mother and Her New‐Born Son

“…Whether or not these pulmonary lesions may be placed in relation to the primary disease, tuberous sclerosis, is impossible to say. Pneumonia would seem to be a far less common cause of death in tuberous sclerosis than the cerebral lesions (including hydrocephalus) or cardiac abnormalities (6).…”