Die Stabilisierung von Malleolarfrakturen und Flakeverletzungen mit Resorbierbaren Polyglykolid-Stiften (Biofix©)

Ruf, W.; Schult, W.; Buhl, K.

doi:10.1007/bf02588776

Cited by 19 publications

(3 citation statements)

References 7 publications

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“…Implantate aus biologisch abbaubaren Kunststoffen wie Polydioxanon (PDS), Polylaktid (PLA) und Polyglykolid (PGA) haben bereits Eingang in die klinische Praxis gefunden [1,2,3,4,5,6,10,11,13,14,15,19,20,24,27,28,31]. Polyglykolide zeigen eine große initiale Festigkeit aber rapide Festigkeitsverluste nach der Implantation sowie eine hohe Rate an Fremdkörperreaktionen bei der klinischen Anwendung [15,18,22,32].…”

Section: Osteosynthesepins · Femurkortikalis · Festigkeitseigenschaftenunclassified

Festigkeitsuntersuchungen an Pins aus humaner Femurkortikalis

Berns¹,

Hofmann²,

Götzen³

2001

Der Unfallchirurg

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For biomechanical evaluation of cortical bone as a potential source for internal fixation devices, pins of 2 and 3 mm in diameter were made from fresh human femora and subjected to bending loads. Some of the pins were tested without further treatment; others were defatted and dried in acetone solution. Of the acetone-treated pins, some were autoclaved either at 121 degrees C for 20 min or at 134 degrees C for 8 min. Acetone treatment of the pins caused a 5.5% increase in bending strength (p < or = 0.05) and a 6.6% increase in the elastic modulus (p < or = 0.05). The mean bending strength of the acetone-treated pins was 257 +/- 52 N/mm2 and the mean elastic modulus was 18,346 +/- 1292 N/mm2. Autoclaving of the pins at the lower temperature for a longer time led to a decrease in the bending strength of up to 16% and at the higher temperature for a shorter time to a decrease of up to 41%. To compare the strengths of the cortical and synthetic pins, 2-mm Biofix pins were also tested. The Biofix pins showed a 25% higher bending strength than the acetone-treated pins but a 12.5% lower elastic modulus. It should be noted that in animal studies the synthetic Biofix pins showed a 20% loss of strength within 2 days after implantation in situ.

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Section: Osteosynthesepins · Femurkortikalis · Festigkeitseigenschaftenunclassified

Festigkeitsuntersuchungen an Pins aus humaner Femurkortikalis

Berns¹,

Hofmann²,

Götzen³

2001

Der Unfallchirurg

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“…Als Osteosynthesematerial werden resorbierbare Stifte seit Anfang der 80 er Jahre in verschiedenen Arbeitsgruppen eingesetzt [7,8,19,23,28,29]. Wa È hrend sich dieses Osteosynthesematerial von rekonstruktiver und funktioneller Seite in klinischen Studien bewa È hrte, kam es bei etwa 10 % zu lokalen Komplikationen.…”

Section: Kombinierte Biofixspickungunclassified

Perspektive der Kirschnerdraht-Osteosynthese bei der dorsal instabilen, distalen Radiusfraktur (Colles-Typ)

Fritz

Klavora

Krieglstein

et al. 1997

Chirurg

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The following experimental study was conducted to develop biocompatible methods of osteosynthesis in fractures of the distal radius and to evaluate their stability. A model of dorsal wedge osteotomy in the distal radial metaphysis was used to develop the surgical technique and to test the stability of the alternative methods of osteosynthesis. The concept for this model was based on commercially available materials which were either biodegradable or osteoconductive. Four different forms of biocompatible osteosynthesis were compared to combined Kirschner wire osteosynthesis (KWO), our preferred method of treatment of unstable Colles fracture. Biocompatible osteosynthesis was achieved with an invasivity and stability comparable to that of KWO. In conclusion, injection osteosynthesis exceeded the other biocompatible methods of osteosynthesis in all respects. Regarding the recent developments in injectable materials for osteosynthesis it offers the best perspective for clinical application.

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“…Soon after the clinical introduction of internal fracture fixation implants that were made of absorbable polyesters, it became obvious that these devices occasionally evoked a delayed abacterial inflammatory reaction (Bostman et al 1987, Ruf et al 1990, Steinmann et al 1990). Upon histopathologic examination, these tissue responses showed the characteristics of a typical nonspecific foreign-body reaction (Bostman et al 1990, Poigenfiirst et al 1990).…”

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confidence: 99%