“…This increase was likewise assumed to be composed of the type III isomer, although it was not isolated. There is also the possibility that some degree of liver functional impairment had occurred with resultant increase of type I rather than type III, an association which has been discussed previously (11), and in favor of which there is abundant evidence in the literature (5,10,(27)(28)(29). It seems less probable, however, that this factor would be important after the simple ingestion of blood by normal individuals, which was reported by Schumm (2), and Fischer (3) to be followed by an increased urinary coproporphyrin of undetermined type.…”