Die Psychopharmakotherapie der schweren Depression unter klinischen Bedingungen

König, Frank

doi:10.1007/978-3-642-60807-0_16

Cited by 2 publications

(1 citation statement)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In principle, however, citalopram proved to be effective in the present study and in an open study with sertindole [29], and paroxetine had already proved to be first-line therapy in the earlier combination with haloperidol and zotepine [4] in severely depressed patients. SSRIs can be used as an alternative to tricyclic antidepressants in severe depressions [19,20]. In the recent psychopharmacological literature, an antipsychotic potency has been postulated for the SSRIs fluvoxamine, paroxetine and sertraline in cases of delusional depression (controlled studies) [10,11].…”

Section: Discussionmentioning

confidence: 99%

First Experiences in Combination Therapy Using Olanzapine with SSRIs (Citalopram, Paroxetine) in Delusional Depression

König

Hippel

et al. 2001

Neuropsychobiology

Self Cite

View full text Add to dashboard Cite

In an open prospective study, 26 patients with delusional depression (mood-congruent psychotic features: DSM-IV 296.4) were treated over 5 weeks with a combination of SSRI (citalopram, n = 22, or paroxetine, n = 4) and the neuroleptic olanzapine. The course of therapy was evaluated with the Hamilton depression scale (HAMD). Not only the total HAMD score, but also the subscores for affectivity and delusional symptoms decreased significantly. After the end of the 5-week combination therapy, 18 out of 26 patients (69%) could be discharged as responders to outpatient treatment. The course of treatment was characterized by excellent tolerance.

show abstract

Section: Discussionmentioning

confidence: 99%