Die Psoriasis Als Stoffwechselproblem

Grütz, O.; Burger, Max M.

doi:10.1007/bf01758495

Cited by 45 publications

(3 citation statements)

References 6 publications

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“…Some still adhere to the probability of a parasitic or infective cause, but it has been rejected by most authorities (Schamberg, 1909). Gans (1952) has reviewed the evidence put forward to support a metabolic aetiology, that of Grutz and Burger (1933) suggesting a disturbance of lipoid metabolism being the most popular. Gans finds no evidence to support these views, and that is the general consensus of opinion.…”

Section: Prognosismentioning

confidence: 99%

The Significance and Management of Psoriasis

Ingram¹

1954

BMJ

113

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Attention having been drawn to this branch of medicine, we might ask ourselves why the skin does not figure more significantly in our medical curriculum and training, in the facilities afforded for hospital and medical practice, and in research. The skin is the one part of the whole organism the physiological and pathological processes of which are clearly displayed to view, and, if careful observation is the basis of clinical practice and of research, here is a training-ground which cannot be equalled.Common sense would seem to urge that, not for the sake of dermatology as a specialty but for the better and easier understanding of medicine as a whole, the doctor in training should be taught to recognize the fundamentals of his subject in the skin. Nothing should happen in the skin which he cannot interpret in general medical terms, and every medical problem should be approached by way of the skin, which has so much to tell. This College will no doubt use its influence in deliberations on the medical curriculum and on hospital accommodation to improve the position of dermatology, which enjoys much less consideration and poorer facilities in.Britain and the Commonwealth than in most other countries. This is only part of the problem of the necessary reorientation of our views regarding the general and the special in medicine in the interests of the patient and for the training of students. It is necessary that men of ability should be attracted to work in dermatology and should reveal truths that lie hidden in the skin and that must bear significantly upon the whole of medicine.

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Section: Prognosismentioning

confidence: 99%

The Significance and Management of Psoriasis

Ingram¹

1954

BMJ

113

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“…The rational for this is the observation that during World War II the incidence of psoriasis decreased [41], the biochemical composition of psoriatic scales and the high blood levels of cholesterol and other lipids in the blood in patients with psoriasis. This therapeutic approach was supported by several laboratory investigations [42,43].…”

Section: History Of the Therapy Of Psoriasismentioning

confidence: 94%

Lepra vulgaris. History of Psoriasis

Burg¹,

Geiges²

2014

J Turk Acad Dermatol

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Background: The history of psoriasis, remains highly speculative for the time before Willan (1757Willan ( -1812, and can be reliably assigned only for the last 200 years. Terms such as "Leprosy", "Impetigo" and "Psora" have been used in the centuries before. Hebra (1806-1880) gave a morphological and nosologic definition, in which also the histopathology appearance was taken into account. In the early 20th century, it was the biochemistry and histochemistry, which provided new insights. In the second half of the 20th century, immunocytochemistry and immunology shed some light on the pathogenetic processes of the disease. At the end of the 20th and at the beginning of the 21st century, it is the triumph of genetics and immunology, which have opened new therapeutic possibilities due to the interesting insights into the pathogenesis of psoriasis. However besides the new therapeutic modalities, which harbor some health and some economic threats, classical approaches still remain valuable tools. AbstractBackground: The history of psoriasis, remains highly speculative for the time before Willan (1757-1812), and can be reliably assigned only for the last 200 years. Terms such as "Leprosy", "Impetigo" and "Psora" have been used in the centuries before. Hebra (1806-1880) gave a morphological and nosologic definition, in which also the histopathology appearance was taken into account. In the early 20th century, it was the biochemistry and histochemistry, which provided new insights. In the second half of the 20th century, immunocytochemistry and immunology shed some light on the pathogenetic processes of the disease. At the end of the 20th and at the beginning of the 21st century, it is the triumph of genetics and immunology, which have opened new therapeutic possibilities due to the interesting insights into the pathogenesis of psoriasis. However besides the new therapeutic modalities, which harbor some health and some economic threats, classical approaches still remain valuable tools.

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“…Although occlusive vascular disease has been reported to be more common in patients with psoriasis than in healthy subjects [9,10], previous studies concerning serum lipid levels in this disease were controversial, the scrum cholesterol of psoriatics being reported to be raised [11][12][13], normal [14][15][16], or lowered [17][18][19]. In a recent study [20], elevated levels of both VLD Land LDL trigly cerides as well as a tendency towards higher VLDL and lower HDL cholesterol levels have been reported in pso riatics, these abnormalities being more pronounced in patients with severe psoriasis.…”

Section: Discussionmentioning

confidence: 99%

Serum Levels of Apolipoproteins AI, All and B in Psoriasis

Martinez¹,

Rodríguez²,

Antunez³

et al. 1989

Dermatology

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Since an increased incidence of occlusive vascular disease has been reported in psoriasis, serum levels of apolipoproteins AI AII and B were determined in 61 patients with the disease and compared with that of 34 healthy controls. No significant differences were found between the two groups. These findings suggest that the ocurrence of thromboembolic disorders in psoriasis is not related to altered levels of apolipoproteins AI, All, B in these patients.

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Die Psoriasis Als Stoffwechselproblem

Cited by 45 publications

References 6 publications

The Significance and Management of Psoriasis

The Significance and Management of Psoriasis

Lepra vulgaris. History of Psoriasis

Serum Levels of Apolipoproteins AI, All and B in Psoriasis

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