Die Prävalenz der chronisch obstruktiven Lungenerkrankung (COPD) in Deutschland

Geldmacher, Henning; Biller, Heike; Herbst, Andreas; Urbański, Krzysztof; Allison, M. J.; Buist, A. Sonia; Hohlfeld, Jens M.; Welte, Tobias

doi:10.1055/s-0028-1105858

Cited by 80 publications

(36 citation statements)

References 21 publications

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“…In good agreement with results from other studies, COPD is a significantly underdiagnosed disease [28,29]. Applying the LLN to define airflow limitation, only 14.3% of adults aged ≥40 years had already been diagnosed, although 26.4% complained of symptoms.…”

Section: Discussionsupporting

confidence: 78%

“…Differences between rural and urban areas concerning smoking habits are well known in Germany, with metropolitan regions having higher proportions of current smokers than rural regions [31]. Even with a relatively high proportion of smokers in our study (45% females and 24% males), the PY number is obviously lower compared with other populations [1,29,32,33]. The high percentage of smokers in northeast Germany is contrasted by a smaller number of cigarettes smoked daily as well as by a higher age when individuals start smoking [31,34].…”

Section: Discussioncontrasting

confidence: 44%

“…To set our results in perspective, comparisons to data reported by the BOLD study are mandatory [1,28,29,30]. In this study, airflow limitation in COPD was exclusively defined by a fixed ratio of FEV 1 /FVC <0.7 after bronchodilation, resulting in a prevalence ranging from 13.3 to 26.1% in Europe and 11.4 to 26.1% in the overall study population [1].…”

Section: Discussionmentioning

confidence: 99%

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Impact of Different Definitions of Airflow Limitation on the Prevalence of Chronic Obstructive Pulmonary Disease in the General Population

Gläser

Schäper²,

Obst³

et al. 2010

Respiration

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Background: Recent surveys report a surprisingly high prevalence of chronic obstructive pulmonary disease (COPD) worldwide. However, there is evidence that the application of a fixed ratio of forced expiratory volume in 1 s (FEV₁) to forced vital capacity (FVC) may result in a relevant misclassification of airflow limitation. Objectives: The definition of airflow limitation does have a significant impact on its prevalence. Methods: Individual values of lung volumes were assessed in comparison to a reference population by applying either a fixed ratio below 0.7 or the fifth percentile of FEV₁ in relation to FVC. Based on a large-scale population-based survey, reference equations for lung volumes were derived by quantile regression analysis based on 1,809 subjects aged 25–85 years. Both functional definitions were applied to calculate the prevalence of airflow limitation. Results: The prevalence of airflow limitation was significantly higher when applying the fifth percentile compared to the fixed ratio of 0.7 for all age groups and both sexes (all 6.7 vs. 1.9%; women 6.7 vs. 1.3%; men 6.6 vs. 2.6%). Almost 26% of the subjects with airflow limitation complained of dyspnea, whereas COPD had not been previously diagnosed by a physician in 87%. Conclusion: The definition of airflow limitation has a major impact on the observed prevalence rates.

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Section: Discussionsupporting

confidence: 78%

Section: Discussioncontrasting

confidence: 44%

Section: Discussionmentioning

confidence: 99%

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Impact of Different Definitions of Airflow Limitation on the Prevalence of Chronic Obstructive Pulmonary Disease in the General Population

Gläser

Schäper²,

Obst³

et al. 2010

Respiration

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“…über 40 Jahre alt [31]. Basierend auf aktuellen Prävalenzangaben für die fortgeschrittene COPD (0,8 % im Alter ≥ 40 Jahre, GOLD Stadien III-IV [13]) oder den fortgeschrittenen Lungenkrebs (76 100, 5-Jahresprävalenz [27] ▶ Australien:50 % drei Monate vor Lebensende mit einem Anstieg auf 65 % in der letzten Lebenswoche [10]. In einer aktuellen multizentrischen Beobachtungsstudie über Patienten mit fortgeschrittenem Lungenkrebs in den USA (n = 450), Frankreich (n = 613) und Deutschland (n = 600) wurde jüngst eine besonders hohe Symptombelastung durch Atemnot (> 90 %) sowie ihr negativer Effekt auf die Lebensqualität dieser Patientengruppe beschrieben [18,19].…”

Section: Hintergrundunclassified

Charakteristika von Palliativpatienten mit Atemnot

Simon

Altfelder

Alt-Epping

et al. 2016

Dtsch med Wochenschr

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Forschung, Kleinmachnow * geteilte Erstautorenschaft Zusammenfassung Hintergrund | Atemnot ist ein häufiges und belastendes Symptom bei Patienten mit fortgeschrittener lebenslimitierender Erkrankung. Das Ziel dieser Untersuchung war die Beschreibung demografischer und klinischer Charakteristika von Patienten mit Atemnot in Deutschland. Methoden | Wir führten eine Sekundäranalyse von Patientendaten der nationalen Erhebung aus spezialisierten stationären Hospiz-und Palliativeinrichtungen von 2006 bis 2008 durch. Die Hospiz-und Palliativ-Erfassung (HOPE) erhebt jährlich prospektiv deutschlandweit u .a. anhand einer validierten Checkliste standardisiert 16 Symptome und Probleme (Schweregrad 0-3).

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“…The meta-analysis of series of randomized studies established that the prevalence of chronic obstructive pulmonary disease in the world and Europe is on average 7,2 %, that is near four million and hundred people suffer from this disease, in city dwellers the prevalence of chronic obstructive pulmonary disease reaches 10,2 %, among men -9,8 % and women -5,6 % respectively, among patients, older than 40 years -10 %, older than 65 years -14,2 %, among smokers -15,4 %, among persons, who never smoked -4,3 %, among persons, who left smoking -10,7 % [4,6,7].…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Chronic Obstructive Pulmonary Disease in Patients With Coronary Heart Disease and Arterial Hypertension

Распутіна

Didenkо

2017

EUREKA: Health Sciences

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The prevalence of chronic obstructive pulmonary disease among patients with cardio-vascular diseases is higher than in general population. At the same time the one of problems of internal medicine is a timely diagnostics of chronic obstructive pulmonary disease. The aim of the work was the study of prevalence of chronic obstructive pulmonary disease among patients with cardio-vascular diseases, especially arterial hypertension and coronary heart disease. Materials and methods. The retrospective analysis of statistical cards of patients, who were on stationary treatment at therapeutic departments, was carried out to estimate the prevalence of combination of chronic obstructive pulmonary disease with arterial hypertension. The target examination of 136 patients was realized for revelation of chronic obstructive pulmonary disease. All patients were interrogated by the original modified questionnaire of assessment of short breath by medical research council (mMRC), test for assessment of chronic obstructive pulmonary disease (CAT) and underwent spirography with bronchodilatation test. Results. It was established, that 10,2 % of patients had the combination of chronic obstructive pulmonary disease with arterial hypertension. Among persons, who were on treatment as to the stable coronary heart disease and had not obstructive disease of respiratory organs in anamnesis, in 26,4 % the chronic obstructive pulmonary disease was diagnosed for the first time.

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Die Prävalenz der chronisch obstruktiven Lungenerkrankung (COPD) in Deutschland

Abstract: COPD is a highly prevalent disease. With regard to the increasing life expectancy and the change of smoking habits of the population, a further increase of morbidity and mortality due to COPD must be expected, especially in women.

Cited by 80 publications

References 21 publications

Impact of Different Definitions of Airflow Limitation on the Prevalence of Chronic Obstructive Pulmonary Disease in the General Population

Impact of Different Definitions of Airflow Limitation on the Prevalence of Chronic Obstructive Pulmonary Disease in the General Population

Charakteristika von Palliativpatienten mit Atemnot

Prevalence of Chronic Obstructive Pulmonary Disease in Patients With Coronary Heart Disease and Arterial Hypertension

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