Die Paramyloidose

Krücke, W.

doi:10.1007/978-3-642-94742-1_6

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1999

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Cited by 25 publications

(2 citation statements)

References 169 publications

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“…The clinicaljndings in primary amyloidosis have been described in detail by several authors (5,6,18,19,31) and therefore only a few of the findings will be commented upon here.…”

Section: Discussionmentioning

confidence: 99%

Peri‐collagenous Amyloidosis A study of 51 cases

Hällén

Rudin

1966

Journal of Internal Medicine

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“…The clinicaljndings in primary amyloidosis have been described in detail by several authors (5,6,18,19,31) and therefore only a few of the findings will be commented upon here.…”

Section: Discussionmentioning

confidence: 99%

Peri‐collagenous Amyloidosis A study of 51 cases

Hällén

Rudin

1966

Journal of Internal Medicine

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“…However, in 1914 Askanazy [1] had called attention to a regular and selective involvement of choroid plexus vessels. Later, vascular depositions in systemic amyloidosis were described in the infundibulum [2,7,25,28] and the area postrema [28]. Such depositions thus seem to occur only in special regions of the brain that lack a tight blood-brain barrier (circumventricular organs) or in structures located outside the barrier, in the choroid plexus.…”

Section: Introductionmentioning

confidence: 99%

Cerebrovascular involvement in systemic AA and AL amyloidosis: a clear haematogenic pattern

Schröder

Linke

1999

Virchows Archiv

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Amyloid deposits in cerebral vessels are common in beta-amyloid diseases (Alzheimer's disease, congophilic amyloid angiopathy, Down's syndrome and hereditary cerebral amyloidosis with haemorrhage of the Dutch type). We report of 20 autopsies on patients who had died with systemic amyloidosis of the AA, Alambda and Akappa types: the brains were examined for the occurrence of amyloid. Vascular amyloid was detected in choroid plexus (in 17 of 20 cases), infundibulum (5 of 8), area postrema (6 of 11), pineal body (3 of 7) and subfornical organ (2 of 3), but not in cortical and leptomeningeal vessels. Immunohistochemical classification of the cerebral amyloid and the systemic amyloid syndrome showed identity proving the same origin of both. The distribution is indicative of a haematogenic pattern of amyloid deposition in systemic amyloidosis and is different from that in Alzheimer's, prion, ATTR and cystatin C diseases. It corresponds to areas of the brain with a "leaky" blood-brain barrier. Additionally, all the cases with AA amyloidosis exhibited an Abeta coreactivity in choroid plexus vessels. In one exceptional case, Abeta reactivity of AA amyloid also occurred outside of the brain.

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Sonstige Erkrankungen der Schädelknochen von gewisser neurochirurgischer Bedeutung

Volland¹,

Kleinsasser²

1960

Handbuch Der Neurochirurgie

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Die Paramyloidose

Cited by 25 publications

References 169 publications

Peri‐collagenous Amyloidosis A study of 51 cases

Peri‐collagenous Amyloidosis A study of 51 cases

Cerebrovascular involvement in systemic AA and AL amyloidosis: a clear haematogenic pattern

Sonstige Erkrankungen der Schädelknochen von gewisser neurochirurgischer Bedeutung

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