Die Nursing Delirium Screening Scale (Nu-DESC) - Richtlinienkonforme Übersetzung für den deutschsprachigen Raum

Lütz, Alawi; Radtke, Frank‐Olaf; Franck, Martin; Seeling, Matthes; Gaudreau, Jean–David; Kleinwächter, Robin; Kork, Felix; Zieb, Anett; Heymann, Anja; Spies, Claudia

doi:10.1055/s-2008-1060551

Cited by 58 publications

(20 citation statements)

References 10 publications

(9 reference statements)

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“…Furthermore, both methods have a different approach. Nu-DESC is a test with external assessment, CAM-ICU needs a reaction and interaction of the patient [21, 24]. …”

Section: Discussionmentioning

confidence: 99%

“…Occurrence of postsurgical delirium (POD) was the dependent variable (i.e., the primary outcome variable), as measured using a combination of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) [20] and the Nursing Delirium Screening Scale (Nu-DESC) [21, 22] twice a day for the first 3 days after surgery (morning and late afternoon). Both screening tools were tested for ICU patients and show high sensitivity and specificity.…”

Section: Methodsmentioning

confidence: 99%

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Acetylcholinesterase and butyrylcholinesterase in cardiosurgical patients with postoperative delirium

et al. 2017

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BackgroundPatients in intensive care units (ICU) are often diagnosed with postoperative delirium; the duration of which has a relevant negative impact on various clinical outcomes. Recent research found a potentially important role of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) in delirium of critically ill patients on non-surgical ICU or in non-cardiac-surgery patients. We tested the hypothesis that AChE and BChE have an impact on patients after cardiac surgery with postoperative delirium.MethodsAfter obtaining approval from the local ethics committee, this mechanistic study gathered data of all 217 patients included in a randomized controlled trial testing non-pharmacological modifications of care in the cardiac surgical ICU to reduce delirium.Delirium was assessed with the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) and the Nursing Delirium Screening Scale (Nu-DESC) twice a day for the first 3 days after surgery. Further outcome variables were somatic laboratory parameters and variables regarding surgery, anesthesia, and postsurgical recovery. 10 μl venous or arterial blood was drawn and AChE and BChE were determined with ChE check mobile from Securetec.ResultsOf 217 patients, 60 (27.6%) developed postsurgical delirium (POD). Patients with POD were older (p = 0.005), had anemia (p = 0.01), and worse kidney function (p = 0.006). Furthermore, these patients had lower intraoperative cerebral saturation (NIRS) (p < 0.001) and higher intraoperative need of catecholamines (p = 0.03). Delirious patients showed more inflammatory response (p < 0.001). AChE and BChE values were mainly inside the norm. Patients with values outside the norm did not have POD more often than others. Regarding AChE and BChE patients did not differ in having delirium or not (p > 0.10).ConclusionsPostoperative measurement of AChE and BChE did not discern between patients with and without POD. The effect of the cardiac surgical procedure on AChE and BChE remains unclear. Further studies with patients in cardiac surgery are needed to evaluate a possible combination of delirium and the cholinergic transmitter system. There might be possible interactions with AChE/BChE and blood products and the use of cardiopulmonary bypass, which should be investigated more intensively.Trial registrationGerman Clinical Trials Register, DRKS00006217

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“…Furthermore, both methods have a different approach. Nu-DESC is a test with external assessment, CAM-ICU needs a reaction and interaction of the patient [21, 24]. …”

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Acetylcholinesterase and butyrylcholinesterase in cardiosurgical patients with postoperative delirium

et al. 2017

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“…Ab einer Gesamtpunktzahl von 2 liegt ein Delir vor. 27 Die Detektion eines SSD gilt als eingeschränkt und kann bei einer einzigen Punktvergabe in Erwägung gezogen werden. Der Score ermöglicht eine Einstufung des Schweregrads.…”

Section: Cam-icu Die Confusion Assessment Methods For the Intensiveunclassified

Dem Delir ein Schnippchen schlagen

Scheunemann¹,

Stuch²

2016

intensiv

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“…Zu den etablierten und validierten Testinstrumenten zählen u. a. ▪ die Nursing Delirium Screening Scale (Nu-DESC) [10,11]…”

Section: Hintergrundunclassified

3D-CAM: Delir-Testinstrument für deutschsprachigen Raum übersetzt

Olbert¹,

Eckert²,

Mörgeli³

et al. 2018

Anästhesiol Intensivmed Notfallmed Schmerzther

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Die Nursing Delirium Screening Scale (Nu-DESC) - Richtlinienkonforme Übersetzung für den deutschsprachigen Raum

Abstract: The German version of Nu-DESC provides an instrument for evaluating the delirium in the area of clinical routine and research.

Cited by 58 publications

References 10 publications

Acetylcholinesterase and butyrylcholinesterase in cardiosurgical patients with postoperative delirium

Acetylcholinesterase and butyrylcholinesterase in cardiosurgical patients with postoperative delirium

Dem Delir ein Schnippchen schlagen

3D-CAM: Delir-Testinstrument für deutschsprachigen Raum übersetzt

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