Die Milzszintigraphie als Methode zur funktionellen Milzanalyse

“…The spleen volume was calculated according to the formula v = 0-3 4a3, where v represented the volume of the spleen in ml and a the largest surface area in cm2 (Fischer, 1970).…”

Section: Methodsmentioning

confidence: 99%

Platelet dynamics in chronic liver disease with special reference to the role of the spleen.

Toghill¹,

Green²,

Ferguson³

1977

J Clin Pathol

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SUMMARY In all of 12 patients with chronic liver disease, whose platelet dynamics were investigated by the 51Cr-labelling technique in association with surface counting, platelet survival was reduced and in Ithe splenic platelet pool was increased. Surface counting showed high initial spleen:liver ratios in eight patients, and in four there was evidence of progressive destruction of platelets in the spleen. In one patient, subsequently shown to have a hepatoma, progressive accumulation of platelets was noted at the tumour site.

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“…The largest spleen area of the posterior or left lateral view was used for the calcula tion of the spleen weight according to the formula w = 0.3 • ^/A5 (w = weight (grams), A = largest scan area (cm2)] as suggested by Fischer [1], After cutting the Polaroid film through the outlines, the area in square millimetres was obtained by weighing this and a standard and converted to square centimetres by means of an enlargement factor.…”

Section: Methodsmentioning

confidence: 99%

“…The purpose of the present study was to compare two different methods for esti mation of spleen size based on either one [1] or two [7] scintigraphic projections of the spleen and to compare these with 'true' spleen weight obtained after splenectomy. Furthermore, the scintigraphic image and the results of physical examination of the abdomen in relation to spleen size were compared.…”

Section: Introductionmentioning

confidence: 99%

“…Of ten the only measure of spleen size used in daily clinical work is based on the physical examination of the abdomen. This meth od, however, is unreliable as even grossly enlarged spleens can be missed [1,2]. Ra dioisotope scintigraphy with visualization of the spleen offers a possibility for an ob jective estimation of spleen size, and var ious formulas for the estimation of the ac tual volume or weight of the spleen from the scintigraphic image have been pro posed [3][4][5][6].…”

Section: Introductionmentioning

confidence: 99%

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Prediction of Spleen Size by Routine Radioisotope Scintigraphy

Ingeberg¹,

Støckel²,

Sørensen³

1983

Acta Haematol

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Technetium-99m scintigraphy of the spleen was performed in 32 patients with various haematologic disorders prior to splenectomy. From the gamma camera image of the spleen, the weight of the spleen was estimated using two different mathematical formulas, and the results obtained were compared to the postoperative spleen weight. Both formulas revealed spleen weights showing highly significant correlations to the postoperative spleen weight and with similar standard deviations. Visual evaluation of the scintigram by an experienced examiner with classification of the spleens into four groups according to spleen weight revealed results as good as the mathematical calculations in predicting the postoperative spleen weight, both techniques giving diagnostic specificities of 0.70–0.80 for all groups and diagnostic sensitivities of 0.80–1.00. Physical examination of the abdomen showed that about 50% of the spleens weighing between 250 and 1,000 g were not palpable. Therefore, it is concluded that physical examination of the abdomen alone is unreliable. Radioisotope scintigraphy of the spleen is recommended, this method being fast, with negligible discomfort to the patient, and with sufficient accuracy for daily clinical work.

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Die Milzszintigraphie als Methode zur funktionellen Milzanalyse

Cited by 24 publications

References 10 publications

Platelet dynamics in chronic liver disease using the 111Indium oxine label.

Platelet dynamics in chronic liver disease using the 111Indium oxine label.

Platelet dynamics in chronic liver disease with special reference to the role of the spleen.

Prediction of Spleen Size by Routine Radioisotope Scintigraphy

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