Die medikamentöse Therapie von Missbrauch und Abhängigkeiten (Tabak, Alkohol und illegale Drogen)

Lesch, Otto-Michael; Platz, Werner E.; Soyka, Michael; Walter, Henriëtte

doi:10.1007/978-3-211-85473-0_18

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“…The revised manuals should include easily assignable items for severity of different arrays (time illness onset, co-morbidity, withdrawal symptoms, bridge symptoms and neurological sequela). Different therapy stages (e. g. withdrawal or relapse prevention) need a different weighting of individual symptoms (e. g. degree of intoxication, severity of withdrawal is needed for acute treatment, while an [24]. International haben sich 2 Klassifikationssysteme (ICD-10 und DSM IV) etabliert, die heute weltweit verwendet werden.…”

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confidence: 99%

“…Im Augenblick, in dem man diese beiden Ziele verlässt (Epidemiologie und Kostenersatz), erweisen sich beide Systeme als viel zu breit und viel zu wenig aussagekräftig, um einen patientengerechten Therapieplan zu entwickeln. Die Ergebnisse der genetischen Forschung, der Basisforschung, aber auch die Therapieforschung (pharmakologisch und psycho-therapeutisch) gelten immer nur für eine Untergruppe der Abhängigen [17,24]. assignment of co-morbidity and personality factors is necessary for relapse prevention).…”

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Die Diagnose Abhängigkeit im DSM V und ICD-11 zum jetzigen Stand der Forschung

Lesch¹

2009

Fortschr Neurol Psychiatr

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Diagnoses are made for identifying rather homogeneous groups of patients being thereby relevant for research and for therapy. Therefore diagnostic manuals, like the DSM-IV and the ICD-10 are subjected to changing knowledge derived from research on one hand and to changes of clinical necessities. The diagnosis of substance related disorders, published for DSM-IV in 1994 and for the ICD-10 in 1992, has proven of value for epidemiological research and economic validation. In spite of these advantages the concept has prove to be too broad and rather unspecific for research, specific therapeutic strategies and for defining an illness course. During the last 20 years research has yielded many criteria of interest, which never entered DSM IV or ICD-10, remaining therefore on the level of single items, which are nowadays additionally assigned to all patients (like e. g. early versus late onset) or on the level of typologies (like e. g. Lesch's typology) demanding different treatments. To give an example: acamprosate has lasting relapse preventing effects in Lesch types I and II, while naltrexone is effective in types III and IV. For rendering an expertise in Germany, the referring literature recommends to utilize Lesch's typology additionally to the ICD-10 diagnosis, especially when prognosis or therapeutic strategies are demanded. Since 1999 different expert groups strive for including new criteria into DSM IV and ICD-10. The revised manuals should include easily assignable items for severity of different arrays (time illness onset, co-morbidity, withdrawal symptoms, bridge symptoms and neurological sequela). Different therapy stages (e. g. withdrawal or relapse prevention) need a different weighting of individual symptoms (e. g. degree of intoxication, severity of withdrawal is needed for acute treatment, while an assignment of co-morbidity and personality factors is necessary for relapse prevention). This quantifier is rendered by Lesch's typology, which is available in the form of a computer programme, based on a decision tree (see also www.ausam.at - Typology according to Lesch). Non substance related disorders should enter other diagnostic categories, like e. g. impulse control disorders. A revised diagnostic classification suggests presently offered therapeutic strategies to follow up with necessary modifications. A tailor made therapy according to subgroups can result in better long term performance of therapies offered to persons suffering form substance related disorders.

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