Die Krampfschädigungen des Gehirns

Pathological Findings in Temporal Lobe Epilepsy

“…Penfield and his collaborators assumed that this anoxia occurred at birth. Against this must be set the widely accepted view elaborated by Spielmeyer and his school, particularly by Scholz (1951Scholz ( , 1953, that Ammon's horn sclerosis in epilepsy results from the functional vascular and anoxic disturbances which accompany (or perhaps precede) severe generalized convulsions.…”

Evolution of Seizure Patterns in Experimental Epilepsy

“…Not only does this case history illustrate the change from psychomotor to focal epilepsy with corresponding EEG changes, but also a remarkable histological finding in that there was selective degenera tion of the right hemisphere. The damage was not in the area where hypoxic damage is most common [41] (i.e. putamen and globus pallidus) but in the hippocampal, entorhinal, and cingulate areas which constitute the major part of the limbic system.…”

Perisulcal infarcts: Lesions caused by hypotension during increased intracranial pressure

“…Twelve years later Scholz [27] changed his interpretation, concluding that the leptomeningeal blood vessels became compressed by increased brain volume while blood flow concurrently decreased during the seizure. Jacob [ 141 described ischemic lesions in the depth of the sulci in 2 patients who had survived 96 hours and eight days, respectively, following strangulation; both had signs of brain edema.…”