Die Gewebsver�nderungen der Haut im Verlaufe des Lebens

Effect of Castration and Peroral Estrogen Therapy on the Skin

“…Hill & Montgomery (1940) observed no connection between age and the histologic structure of collagenous and elastic fibres. But Strobel ( 1948), too, reported that degeneration of collagen was typical of old age; the collagen bundles became thinner and sparser. According to Ma & Cowdry (1960), it was possible to establish histologically a decreasing of elastic tissue in old skin.…”

“…The epidermis is thinned in old age and the basal layer becomes even (M. A. Goldzieher, 1946;Cowdry et al, 1947;Strobel, 1948;Kodama, 1962). Wells ( 1954) is of the opinion that this evening of the basal layer is a secondary phenomenon caused by atrophy of the dermal papillae.…”

“…According to Strobel ( 1948), the epidermis begins to atrophy gradually after the 30th year of age. The atrophy is intensified between 40 and 50, the epidermis-dermis boundary is almost straight and the rete pegs are decreased.…”

Resection force analysis of 1 and 2 mm punch biospies combined with rotation on temperature-controlled cadaver skin use for the acquisition of full skin islets for skin transplantation

“…In 1947 Stroebel recognised a relationship between tissue changes and the age of the skin. Skin aging already begins in mid-life and is associated with changes occurring in collagen fibres located within the dermis [5]. Accordingly, the number of collagen fibres starts to decrease from the age of 30.…”

Senile Changes of the Skin in Man

“…There appears to be a diminution in total bulk of collagen in old age and Strobel (14) found that the fiber bundles showed packing into parallel arrays more prominently in old skin. These changes are not easy to appreciate under the microscope and some observers have doubted that any consistent diminution of fibers could be demonstrated.…”