Die Eklampsie im Lichte hirnelektrischer Untersuchungen

Janzen, R. W. C.; Schroeder, C; Heckel, H

doi:10.1007/bf01471891

Cited by 6 publications

(1 citation statement)

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“…The electroencephalogram (EEG) is sensitive enough to distinguish if an intra-partum seizure has resulted from eclampsia or if the mother suffered an epileptic seizure during labor (244, 245). Furthermore, hypertensive PE and eclamptic women exhibit changes in EEG recordings compared to normotensive pregnant and non-pregnant females (244).…”

Section: Cerebrovascular and Higher Function Neurological Consequencementioning

confidence: 99%

Preeclampsia and the brain: neural control of cardiovascular changes during pregnancy and neurological outcomes of preeclampsia

2016

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Preeclampsia (PE) is a form of gestational hypertension that complicates ~ 5 percent of pregnancies worldwide. Over 70 percent of the fatal cases of PE are attributed to cerebral edema, intracranial hemorrhage, and eclampsia. The etiology of PE originates from abnormal remodeling of the maternal spiral arteries, creating an ischemic placenta that releases factors that drive the pathophysiology. An initial neurological outcome of PE is the absence of the autonomically regulated cardiovascular adaptations to pregnancy. PE patients exhibit sympathetic overactivation, in comparison to both normotensive pregnant and hypertensive non-pregnant females. Moreover, PE diminishes baroreceptor reflex sensitivity (BRS) beyond that observed in healthy pregnancy. The absence of the cardiovascular adaptations to pregnancy, combined with sympathovagal imbalance and a blunted BRS leads to life-threatening neurological outcomes. Behaviorally, the increased incidences of maternal depression, anxiety, and post-traumatic stress disorder (PTSD) in PE are correlated to low fetal birth weight, intrauterine growth restriction (IUGR) and premature birth. This review addresses these neurological consequences of PE that present in the gravid female both during and after the index pregnancy.

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Section: Cerebrovascular and Higher Function Neurological Consequencementioning

confidence: 99%