Die Einstellung des Fließgleichgewichtes von Inulin im extracellulären Raum

Eppler, Friedrich; Harth, O.; Kreienberg, Walter; Mertz, D. P.

doi:10.1007/bf02045820

Search citation statements

Order By: Relevance

Paper Sections

Select...

Pharmacokinetic System Identification1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

1956

1995

Publication Types

Select...

Article6

Relationship

Self Cite0

Independent6

Authors

Journals

Cited by 9 publications

(1 citation statement)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Therein the extracellular space is considered to be composed of two functionally separated spaces, a well perfused central volume and a less perfused peripheral compartment. The marker kinetics, represented by the temporal courses of the marker amounts in the two compartments, is the result of the infusion strategy, the exchange transports between the two compartments, and finally the renal elimination process (20)(21)(22)(23).…”

Section: Pharmacokinetic System Identificationmentioning

confidence: 99%

Determination of the Glomerular Filtration Rate by Identification of Sinistrin Kinetics

Estelberger

Petek²,

Zitta³

et al. 1995

CCLM

View full text Add to dashboard Cite

Summary: A computer-based method of system identification and estimation of parameter variance for two-compartment models matched to dynamic sinistrin concentration profiles for the determination of glomerular filtration rate is described. Thereby a procedure for the judgment of the optimal sampling time horizon is presented. Since single-injection techniques are suspected of yielding systematic overestimation of the glomerular filtration rate, a method is demonstrated confirming that such a technique employing sinistrin kinetics can be used to correctly determine the glomerular filtration rate.

show abstract

Section: Pharmacokinetic System Identificationmentioning

confidence: 99%