Die Bufogenine des Paratoidensekretes von Bufo arenarum HENSEL. Über Krötengifte, 20. Mitteilung

Abstract

Phriz).l-I-cyclopantane-caPboxylafe d'ithyle[ X X X I , n = 21. Xous avons utilisC le procCd6 dc Phdii~l-1-cyclopropaize-carboxylate d'e'thyle [ X X X I . n = 01. I1 a CtC prCpar6 par un procede analogue; ICb. 117-118"/11 Torr ( K O N D O~) , Eb. 129-133"/21 Torr), nZ3 = 1,5085, rdt. 66%. (Ph~ir~l-l'-cvclopentyl-7')-mCthanol [ X X X I I , tab. 31 c t (phdnyl-7'-cyclopropyl-1')-me'thanol~S X X I V , t a b . 31. Synth6tisCs par rCduction des cstcrs correspondants par le hutylate sodique.T.cs carbamates correspondants [ X X X I I I et XXX\', tab. 31 ont CtC prCparCs par la mCthodc -1 tlCcritc antCricurcnicxit'a). \ ' 4 N H E Y X I N C E N ' ) ; Rb. 142-144"/10 Torr, I120 = 1,5145. rdt. 90?". RESIJMCLa synthcse de trois sCries de dCrivCs du (propyn-2'-yl-lr)-l-cyclohexanol-l (A) r.;t dCcrite et leur activitC hypnotique d6terminCe.

Pharmacology and toxicology of toad venom

“…In all instances the lactone ring is 6-membered of a-pyrone type, attached CINOEUFOTALIN plant origin is exemplified by several species (37)(38)(39). When the means are converted to their reciprocals, they become the number of LD'Cper mg. as given in Table I, expressing the direct relationship of activity.…”

MALDI‐MS argininyl bufadienolide esters fingerprint from parotoid gland secretions of Rhinella arenarum: Age, gender, and seasonal variation

“…Chemical composition of secretion produced by R. arenarum was studied for the first time by in 1933 by Chen et al and described the presence of arenobufagin, arenobufotoxin, and arenobufotenin in the alcoholic extract . Later, Rees et al (1959) characterized some bufogenins using IR spectroscopy in parotoid secretions . More recently, Maciel et al (2003) studied indolealkylamines by TLC and ESI‐MS in extract from secretions .…”