Die Bildung von Calciumoxalat-Mikrosteinen im menschlichen Harn und ihre Veränderung durch diätetische und medikamentöse Maβnahmen

Sengbusch, Reinhold von; Timmermann, Albert

doi:10.1159/000277315

Cited by 18 publications

(5 citation statements)

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“…A relative increase in oxalate concentration results in a rise in the proportion of calcium oxalate monohy drate. Other experimental and clinical observations indi cate that this principle holds good even in vivo [6,7,14].…”

Section: Resultsmentioning

confidence: 98%

A Gel Model for Measuring Crystallization Inhibitor Activities

Schneider¹,

Bothor²,

Berg³

et al. 1983

Urol Int

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We devised a simple and economical technique for measuring crystallization inhibitory activities. Calcium ions and oxalate ions diffuse towards one another from two adjacent wells in a layer of gel on a microscope slide. Where they meet, a streak of calcium oxalate crystals forms. Substances which influence crystallization are caused to diffuse into this middle zone. Depending on the inhibitory potency of the substance, the calcium oxalate streak varies in density and extent. These differences are recorded photometrically by comparison with a sample containing no inhibitor, and the inhibition index is calculated. Some of the best known inhibitors were tested and showed a definite effect in this model. Magnesium and citrate in physiological concentrations are of special significance. The expected range of variation of inhibitory activities in human urine is covered by this method.

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Section: Resultsmentioning

confidence: 98%

A Gel Model for Measuring Crystallization Inhibitor Activities

Schneider¹,

Bothor²,

Berg³

et al. 1983

Urol Int

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“…Sengbusch and Timmermann (10) showed increased urinary excretion of calcium oxalate crystals in mono-and dihydrate form after increasing the intake of oxalate-con taining foods by mouth.…”

Section: Introductionmentioning

confidence: 99%

Experimental Urinary Stone Formation following Persorption

Rost¹,

Brosig²,

Riedel³

et al. 1975

Eur Urol

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“…Oxalsäurcbelastung nach Spinat-oder Rhabarbergenuß führt zu einer vermehrten, teilweise sogar massiven Oxalat-Kristallausschcidung bei Gesunden (17,18,19,22,23). Je nach Kostform wurde ein qualitativer und quantitativer Unterschied der einzelnen Oxalat-Kristallformen beobachtet.…”

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“…Je nach Kostform wurde ein qualitativer und quantitativer Unterschied der einzelnen Oxalat-Kristallformen beobachtet. Man kennt im Urinsediment die Oxalsäure-Monohydratformen oder Whewellit-Kristalle und die Dihydratformcn oder Wedellit (18,19). B u t t und Mitarb.…”

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