Did the subjects and the controls have the same disease?

Simultaneous and multisite tumor rapid-target bioimaging through in vivo biosynthesis of fluorescent gold nanoclusters

“…These ultrasmall particles with nite cluster size, termed nanoclusters, present molecular-like electronic transitions between HOMO and LUMO energy levels. 1,2 Besides the unique electronic nature of gold-based nanocomposites, intriguing physical and chemical properties are promising in these nanomaterials, and obtain new opportunities for optical and biomedical applications, [3][4][5][6] including imaging, biosensing, diagnostics, and therapy. 7,8 Recent research indicates that nanoparticle-based imaging could be used for molecular imaging of tumor microenvironment and image-guided interventions including drug delivery, surgery and ablation therapy, especially uorescence GNCs, exhibit a great potential for the tumor target imaging in vitro and in vivo.…”