Dichotomous responses of inter and postprandial hyperglycaemia to short‐term calorie restriction in patients with type 2 diabetes

Colette, C; Ginet, Christine; Boegner, C.; Bénichou, M.; Pham, T. C.; Cristol, Jean‐Paul; Monnier, L.

doi:10.1111/j.1365-2362.2005.01482.x

Cited by 15 publications

(4 citation statements)

References 30 publications

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“…Similarly, in another study dietary glycemic excursions were observed after meals on CGM graphs of individuals with T2DM. 23 Glucose levels in that study were examined 4 h after meals (postprandial) and at all other times (interprandial) before and after an 18-day calorie-restricted diet. Caloric restriction significantly improved interprandial hyperglycemia but did not affect postprandial glucose excursions after breakfast.…”

Section: Discussionmentioning

confidence: 99%

“…Caloric restriction significantly improved interprandial hyperglycemia but did not affect postprandial glucose excursions after breakfast. 23 CGM data may provide opportunities for developing individualized treatment plans, including the content and timing of meals and exercise. Future studies are needed to determine if behavior change following counseling is evident on a repeat CGM study.…”

Section: Discussionmentioning

confidence: 99%

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Continuous Glucose Monitoring in Non–Insulin-Using Individuals with Type 2 Diabetes: Acceptability, Feasibility, and Teaching Opportunities

Allen

Fain

Braun

et al. 2009

Diabetes Technology & Therapeutics

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Background: Continuous glucose monitoring (CGM) has the potential to provide useful data for behavioral interventions targeting non-insulin-using, sedentary individuals with type 2 diabetes mellitus (T2DM). The aims of this study were to describe CGM in terms of (1) feasibility and acceptability and (2) dietary-and exerciseteaching events. Methods: Cross-sectional data were analyzed from 27 non-insulin-using adults with T2DM who wore CGM for 72 h as part of a larger study on using CGM for exercise counseling in this population. Feasibility data included accuracy of entering daily self-monitored blood glucose (SMBG) readings and events (e.g., meals, exercise), sensor failures, alarms, optimal accuracy of glucose data, and download failures. Acceptability data included CGM satisfaction and wearing difficulties. Dietary-and exercise-teaching events were identified from CGM and activity monitor data. Results: CGM graphs showed 141 dietary-and 71 exercise-teaching events. About half the participants (52%) reported difficulty remembering to enter events into CGM monitors, but most (82%) kept an accurate paper log of events. Insufficient SMBG entries resulted in 32 CGM graphs with "use clinical judgment" warnings. Eighty-three percent of missed SMBG entries were from 18 participants 55-77 years old. Missing correlation coefficients resulted from glucose concentrations varying Ͻ100 mg/dL. A majority of participants (n ϭ 19) were willing to wear CGM again despite reporting minor discomfort at sensor site and with wearing the monitor. Conclusions: CGM data provided several teaching opportunities in non-insulin-using adults with T2DM. Overall, CGM was acceptable and feasible. Some identified problems may be eliminated by newer technology.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Continuous Glucose Monitoring in Non–Insulin-Using Individuals with Type 2 Diabetes: Acceptability, Feasibility, and Teaching Opportunities

Allen

Fain

Braun

et al. 2009

Diabetes Technology & Therapeutics

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“…The HbA1c levels of the ZDF rats in this study were 10% or more. Also, in patients with poor glycemic control and more than 9.3% HbA1c, the contribution ratio of the suppressed postprandial blood glucose level for HbA1c is low; approximately 40% (16). In other words, HbA1c shows a stronger relationship with fasting blood glucose level than with postprandial blood glucose (17,18).…”

Section: Discussionmentioning

confidence: 99%

Combined Effects of a Dietary Fiber Mixture and Wheat Albumin in a Rat Model of Type 2 Diabetes Mellitus

Kubo

Koido

Kitano

et al. 2016

J Nutr Sci Vitaminol

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Summary As bioactive ingredients of functional foods, dietary fiber and wheat albumin (WA) are known to suppress hyperglycemia in patients with type 2 diabetes mellitus. The combined effects of these bioactive ingredients were examined using an animal model of type 2 diabetes mellitus. First, oral starch tolerance tests (OSTTs) with the simultaneous intake of a dietary fiber mixture (DF) and WA were performed as an acute study. Male GotoKakizaki rats received a soluble starch solution [700 mg/kg body weight (bw)] containing DF and/or WA (each 300 mg/kg bw). In these OSTTs, the combined intake of DF and WA suppressed hyperglycemia much more effectively than each separate intake. Second, in a chronic intake study, diets containing DF and/or WA were administered to male Zucker diabetic fatty rats over 84 d. The combined effects of DF and WA were not observed in glycosylated hemoglobin concentration levels or fasting blood glucose levels, but appeared as an improvement in liver lipid contents. Variations in the liver lipid contents were similarly reflected in those of the plasma lipid concentrations. In conclusion, this study found that the simultaneous intake of bioactive DF and WA improved the postprandial hyperglycemia and the chronic lipid metabolism disorders in rat models of type 2 diabetes mellitus. Key Words type 2 diabetes mellitus, dietary fiber, wheat albumin, combined effect, lipid metabolism disorderIn type 2 diabetes mellitus, postprandial hyperglycemia caused by a lack of prompt insulin secretion is closely associated with insulin resistance and thus hyperglycemia, which leads to a lipid metabolism disorder that results in arteriosclerosis (1-3). Some dietary fiber, such as water-soluble dietary fiber, physically retards the absorption of glucide and suppresses postprandial hyperglycemia (4). In Japan, therefore, the dietary fibers extracted mostly from various plants are used as functional ingredients of foods. On the other hand, wheat albumin (WA), based on the action of its principle component 0.19-albumin (termed by its electrophoretic mobility), inhibits mammalian amylase (5, 6), delays glucide digestion in vivo, and suppresses postprandial hyperglycemia (7). Thus, WA is widely distributed as a bioactive ingredient of food for specified health uses (FOSHU) in the market. Various consumers, intentionally or unintentionally take simultaneously more than two of these functional ingredients in foods. However, the combined effects of dietary fiber and WA on the postprandial hyperglycemia and also on chronic glucide and lipid metabolism are unknown. Here the simultaneous intake of these ingredients was examined using a rat model of type 2 diabetes mellitus. MATERIALS AND METHODSApproval and feeding conditions. All rats were maintained under standard conditions of 2362˚C and 55615% humidity with a 12 h/12 h light/dark cycle. The rats were individually housed in clean cages with free access to water and basal diet (CLEA rodent diet CE-2; CLEA Japan, Inc., Tokyo, Japan) ad libitum during the acclimation p...

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“…A restrição calórica exerce um efeito benéfico no que diz respeito à resistência à insulina em indivíduos obesos; no entanto, a literatura não é clara a respeito da glicemia em indivíduos saudáveis submetidos à restrição alimentar. Alguns pesquisadores defendem que a melhora na sensibilidade à insulina associada à restrição alimentar é atribuída em parte à supressão de produção da glicose hepática (COLETTE et al, 2005;FABBIANO, SUÁREZ-ZAMORANO & RIGO, 2016;LEE et al, 2014).…”

Section: Glutaminaunclassified

Avaliação do controle da expressão gênica de citocinas pró inflamatórias mediado pela IL-10. Participação da IL-10 na modulação da resposta inflamatória exercida pela glutamina e na restrição alimentar

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Dichotomous responses of inter and postprandial hyperglycaemia to short‐term calorie restriction in patients with type 2 diabetes

Cited by 15 publications

References 30 publications

Continuous Glucose Monitoring in Non–Insulin-Using Individuals with Type 2 Diabetes: Acceptability, Feasibility, and Teaching Opportunities

Continuous Glucose Monitoring in Non–Insulin-Using Individuals with Type 2 Diabetes: Acceptability, Feasibility, and Teaching Opportunities

Combined Effects of a Dietary Fiber Mixture and Wheat Albumin in a Rat Model of Type 2 Diabetes Mellitus

Avaliação do controle da expressão gênica de citocinas pró inflamatórias mediado pela IL-10. Participação da IL-10 na modulação da resposta inflamatória exercida pela glutamina e na restrição alimentar

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