Dichloridobis[3-(4-methoxyphenyl)-2-methyl-5-(piperidin-1-yl)-2,3-dihydro-1,2,4-oxadiazole-κN⁴]platinum(II)

Abstract

In title compound, [PtCl2(C15H21N3O2)2], the PtII cation, located on an inversion center, is coordinated by two Cl− anions and two 3-(4-meth­oxy­phen­yl)-2-methyl-5-(piperidin-1-yl)-2,3-di­hydro-1,2,4-oxa­diazole ligands in a distorted Cl2N2 square-planar geometry. The di­hydro­oxa­diazole and piperidine rings display envelope (with the non-coordinating N atom as the flap atom) and chair conformations, respectively. In the crystal, weak C—H⋯Cl hydrogen bonds link the mol­ecules into supra­molecular chains running along the b axis. The piperidine ring is disordered over two positions with the occupancy ratio of 0.528 (4):0.472 (4).

Zinc(ii)-mediated generation of 5-amino substituted 2,3-dihydro-1,2,4-oxadiazoles and their further ZnII-catalyzed and O2-involving transformations

“…62 The X-ray data for these four species represent the second example of structurally characterized metal-free DHODs and the first example of crystallographically characterized 5-aminosubstituted DHOD. Only one work reported metal-free structures of DHODs, 61 whereas more examples of structurally characterized metal-bound DHODs were previously reported and these structures include DHOD complexes of Pd II , 16 Pt II , 14,15,[19][20][21][26][27][28][63][64][65] Pt IV , 19,21 and closo-decaborate clusters bearing the DHOD moiety. 46,66 Zn II -Catalyzed and O 2 -involving transformations of DHODs…”

“…2 ) giving complexed DHODs. [14][15][16]27,28 All these metal-involved reactions have some disadvantages with regard to the preparation of DHODs. In particular, the cycloaddition requires a stoichiometric amount of a metal source (viz.…”

Copper(I)-Catalyzed 1,3-Dipolar Cycloaddition of Ketonitrones to Dialkylcyanamides: A Step toward Sustainable Generation of 2,3-Dihydro-1,2,4-oxadiazoles

“…8 The preparation of metal-free DHODs via routes (D)–(E) requires an additional step (E) of ligand liberation. 1d,8a−8i,9 This method (D–E), despite its generality, employs rather expensive platinum and palladium species.…”

“…These metal-involving methods were applied for generation of DHODs, and it appeared that some metals act as efficient activators of RCN dipolarophiles in the CA (D) . The preparation of metal-free DHODs via routes (D)–(E) requires an additional step (E) of ligand liberation. ,− , This method (D–E), despite its generality, employs rather expensive platinum and palladium species.…”