Diastolic Time during Exercise in Normal Subjects and in Patients with Coronary Artery Disease

Ferrò, Giuseppe; Giunta, Anna; Maione, S; Carella, G; Genovese, Arturo; Chiariello, Massimo

doi:10.1159/000173681

Cited by 20 publications

(9 citation statements)

References 11 publications

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“…Moreover, in a previous report [22], we were able to demonstrate, by STI evaluation recorded continuously during exercise, an ab normal decrease of the diastolic time in re sponse to stress in CAD patients and we hypothesized that this event may play an important role in determining a further re duction of the subendocardial perfusion of the myocardium.…”

Section: Perspectives O F Implementation O F This Techniquementioning

confidence: 72%

Systolic Time-Interval Evaluation by Thermistor Plethysmography during Uninterrupted Dynamic Stress Test in Normals and in Patients with Coronary Artery Disease

Ferrò¹,

Giunta²,

Maione³

et al. 1983

Cardiology

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18 patients with coronary artery disease (CAD) and 21 normal subjects underwent a triangular bicycle exercise test. Systolic time intervals (STI) were calculated at rest and every 2 min during exercise. Under resting conditions, STI were similar in the two groups. During exercise, the ejection time index (ETI), i.e. left ventricular ejection time (LVET) corrected for HR, rose significantly more in CAD patients, as compared to normals. Pre-ejection period (PEP) was also differently affected by exercise in CAD patients, who showed a more shortened PEP (p < 0.001) in the early stage of dynamic stress. PEP/LVET ratio, which in the control group decreased continuously, in CAD patients fell during exercise at lower work loads (p < 0.001), whilst rose during strenuous exercise. Finally, significant differences (p < 0.001) were found in the percent change (%Δ) PEP/LVET ratio between the two groups during the early phase of exercise, in which no superimposition of single values was present. Therefore, this last parameter seems the most reliable to differentiate clearly CAD patients from normal subjects, but its use must be limited at early exercise.

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Section: Perspectives O F Implementation O F This Techniquementioning

confidence: 72%

Systolic Time-Interval Evaluation by Thermistor Plethysmography during Uninterrupted Dynamic Stress Test in Normals and in Patients with Coronary Artery Disease

Ferrò¹,

Giunta²,

Maione³

et al. 1983

Cardiology

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“…The discrepancy between heart rate and diastolic time may be justified considering that this parameter is multifactorially deter mined [9][10][11][12], Heart rate is the main determi nant, but other factors such as preload, after load. cardiac inotropism.…”

Section: Discussionmentioning

confidence: 99%

Diastolic Perfusion Time and Exercise Posture in Coronary Artery Disease Patients: Correlation with ST Segment Changes

Spinelli¹,

Ferrò²,

Duilio³

et al. 1992

Cardiology

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The relationship between either heart rate or diastolic time and ST segment depression has been evaluated during supine and upright exercise in 16 coronary artery disease patients. Diastolic perfusion time and ST segment depression were related by a linear regression, which was independent of exercise posture. The entity of ST segment depression was greater during supine than in upright exercise for the same heart rate. The assessment of the relationship between heart rate and diastolic perfusion time during two exercises showed that at the same heart rate, diastolic perfusion time was shorter in supine posture. In conclusion, the greater entity of ST segment depression induced by supine rather than upright exercise might be explained by the effect of supine posture on diastolic perfusion time.

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“…One of the diagnostic methods is an exercise test. Research suggests that an involvement of the ratio of systolic and diastolic duration (S/D-ratio) can increase the diagnostic value of the exercise test [6][7][8]. However it is also the test with the lowest sensitivity [3][4][5].…”

Section: Introductionmentioning

confidence: 99%

“…Compared to myocardial scintigraphy, heart CT-scanning and Coronary Angiography, exercise test has the lowest cost and amount of side-effects [2]. S/D-ratios during rest show no significant difference between healthy people and people with IHD, but during pulse elevation differences in S/D-ratios occur as a result of longer systole length in people with IHD than in people without IHD [6]. Research suggests that an involvement of the ratio of systolic and diastolic duration (S/D-ratio) can increase the diagnostic value of the exercise test [6][7][8].…”

Section: Introductionmentioning

confidence: 99%

Phonocardiographic Recordings of First and Second Heart Sound in Determining the Systole/Diastole-Ratio during Exercise Test

et al. 2011

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The objective was to examine whether a microphone can be used to detect first and second heart sound during an exercise test and if these recordings can be used to calculate S/D-ratios in healthy subjects. Furthermore the objective was to describe the changes in systolic and diastolic duration under cardiac stress.Nine healthy subjects (5M, 4F) completed a standardized exercise test while wearing a Panasonic microphone incorporated in a specially designed coupler. Recordings of heart sounds were made with Acarix Data Acquisition System at the end of each workload level.As heart rate increased, the recordings became more difficult to interpret as did detection of first and second heart sounds. Recordings from female subjects were easier to interpret than those of male subjects. As heart rate increased, the S/D-ratio increased accordingly. The development of systole and diastole duration was very similar in male and female subjects.First and second heart sound can be detected using a microphone, but noise at higher load levels necessitates the development of a noise-reducing filter. Furthermore the duration of systole and diastole was found altered during stress. The systole duration decreased minimally whilst the diastole duration decreased markedly as a function of higher heart rate.clear heart sound recordings at higher load levels. Possibly a further development of signal filtering can increase the interpretability of heart sound recordings.

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Diastolic Time during Exercise in Normal Subjects and in Patients with Coronary Artery Disease

Cited by 20 publications

References 11 publications

Systolic Time-Interval Evaluation by Thermistor Plethysmography during Uninterrupted Dynamic Stress Test in Normals and in Patients with Coronary Artery Disease

Systolic Time-Interval Evaluation by Thermistor Plethysmography during Uninterrupted Dynamic Stress Test in Normals and in Patients with Coronary Artery Disease

Diastolic Perfusion Time and Exercise Posture in Coronary Artery Disease Patients: Correlation with ST Segment Changes

Phonocardiographic Recordings of First and Second Heart Sound in Determining the Systole/Diastole-Ratio during Exercise Test

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