Diastolic Hibernation Masquerading as Constrictive Pericarditis

Abstract

Diastolic hibernation may therefore represent a unique form of surgically correctable restrictive cardiomyopathy.

Protein Kinase C in Normal and Pathologic Myocardial States

“…Other investigators have subsequently corroborated this finding [137][138][139][140][141]. Another relevant I/R insult is cardiac bypass, and while modern cardioplegia certainly helps to protect the myocardium against I/R injury [142], contractile dysfunction still exists postbypass [40,41]. Acting as an inflammatory stimulus, cardiopulmonary bypass has been reported to increase TNF-␣ mRNA in the white cells [143] and serum levels of TNF-␣ itself [144 -146].…”

p38 MAPK Inhibition Decreases TNF-α Production and Enhances Postischemic Human Myocardial Function

“…After this time, the trabeculae were gradually stretched to a resting force of 1 g, which we have previously determined to be the optimal length-tension for human atrial trabeculae in our laboratory [2,10,[15][16][17][18][19][20][21][22][23][24][25]. Field stimulation was accomplished with platinum electrodes (Radnoti Glass, Inc. Monrovia, CA) at a frequency of 1 Hz.…”

“…Experimental design. Isolated crystalloid-superfused human atrial trabeculae were examined as previously described [2,10,[15][16][17][18][19][20][21][22][23][24][25]. All trabeculae were subjected to a 90-min equilibration period to allow for stabilization of developed force, and subsequently these experiments were conducted for 180 min.…”