Diastolic heart failure and left ventricular diastolic dysfunction: What we know, and what we don't know!

Shammas, Rony L.; Khan, Nazim Uddin Azam; Nekkanti, Rajasekar; Movahed, Assad

doi:10.1016/j.ijcard.2006.03.027

Cited by 29 publications

(22 citation statements)

References 71 publications

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“…Cardiac remodeling has functional consequences by which cardiovascular risk is increased. These consequences are related to the individual aspects such as age, 24 hours blood pressure, the rigidity of blood pressure, plasma volume, neuro-hormonal status, genetic aspects [2,3]. Ventricular hypertrophy involves both myocytes and interstitial tissue.…”

Section: How Does Diastolic Heart Failurementioning

confidence: 99%

“…Signs and symptoms of congestive heart failure include paroxysmal nocturnal dyspnea, orthopnea, gallop sounds, lung crepitations, pulmonary edema, and peripheral edema [3].…”

Section: How To Diagnose Diastolic Heart Failurementioning

confidence: 99%

“…Nevertheless there are studies that attempt to show the role of Nebivolol in the treatment of diastolic heart failure [1,3].…”

Section: How To Treat Diastolic Heart Failurementioning

confidence: 99%

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Treatment of Diastolic Heart Failure in Hypertensive Diabetic Patient - Between Illusion and Achievements

Lucia¹

2014

J Diabetes Metab

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Section: How Does Diastolic Heart Failurementioning

confidence: 99%

“…Signs and symptoms of congestive heart failure include paroxysmal nocturnal dyspnea, orthopnea, gallop sounds, lung crepitations, pulmonary edema, and peripheral edema [3].…”

Section: How To Diagnose Diastolic Heart Failurementioning

confidence: 99%

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Treatment of Diastolic Heart Failure in Hypertensive Diabetic Patient - Between Illusion and Achievements

Lucia¹

2014

J Diabetes Metab

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“…3,4 With regard to the former, it has been shown that nearly half of all patients with congestive heart failure have preserved systolic function. 9,10 The symptoms of exertional dyspnea in these patients often originate from elevated LV diastolic filling pressure which stems from worsening diastolic dysfunction during exercise. 9 -11 This in turn increases pulmonary capillary pressures and subsequently results in dyspnea.…”

Section: Alternative Causes Of Unexplained Exertional Dyspneamentioning

confidence: 99%

Use of Bicycle Exercise Echocardiography for Unexplained Exertional Dyspnea

Singhal

Yousuf

Weintraub

et al. 2009

Clinical Cardiology

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Unexplained exertional dyspnea is a common and perplexing clinical problem. Myocardial ischemia and left ventricular systolic dysfunction are important cardiac causes, but are often not detected in these patients. Recently, exercise-induced left ventricular diastolic dysfunction and exercised-induced pulmonary hypertension have emerged as common alternative mechanisms. While conventional exercise treadmill echocardiography effectively diagnoses left ventricular systolic dysfunction and myocardial ischemia, it has limited ability to detect exercise-induced diastolic dysfunction or pulmonary hypertension. The latest advances in exercise echocardiography, including utilization of tissue Doppler imaging and harmonic imaging, make noninvasive evaluation of both conventional and alternative cardiac causes of exertional dyspnea possible. These advancements, when coupled with newly designed supine exercise platforms for bicycle exercise echocardiography (BE), facilitate the detection of exercise-induced diastolic dysfunction and pulmonary hypertension. Moreover, BE using supine ergometry additionally permits the dynamic evaluation of valvular function and interatrial shunting and detection of pulmonary arteriovenous fistula, uncommon but important causes of unexplained exertional dyspnea. Therefore, we propose that because of its superior diagnostic capabilities, BE should be included as part of a comprehensive cardiac evaluation of patients with unexplained exertional dyspnea.

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“…13,[16][17][18][19][20] This wide range likely reflects not only the unique characteristics of the communities investigated, but also the lack of a consistent definition of diastolic heart failure and the variability of the cutoff point for what is considered a normal or near normal ejection fraction. 21,22 The factors most often found to be associated with the development of diastolic heart failure include increasing age, female sex, hypertension and atrial fibrillation. 3,18,[23][24][25] Although there is some discrepancy regarding the risk posed by coronary artery disease, its prevalence among patients with diastolic heart failure is generally lower than it is among patients with systolic heart failure and higher than it is among healthy controls.…”

mentioning

confidence: 99%