Abstract:In this study, a facile and versatile procedure for the synthesis of a chalcone derivate that a functionalized (E,Z)-2-(4-aminobenzylidene)acenaphthylen-1(2H)-one, 4 was synthesized and also characterized by using FT-IR, NMR and MS. A new HPLC method for the separation of its diastereomers was developed by using a chiral column that contains the amylose tris(3,5dimethylphenylcarbamate) as a chiral selector since it is effective, reproducible and can be used for preparative purposes. High percentage recovery cl… Show more
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