RSC Adv.
 2022
DOI: 10.1039/d1ra09298g
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Diastereoselective synthesis of new zwitterionic bicyclic lactams, scaffolds for construction of 2-substituted-4-hydroxy piperidine and its pipecolic acid derivatives

Enrique Reyes-Bravo
1
,
Dino Gnecco
2
,
Jorge R. Juárez
3
et al.

Abstract: The synthesis of new chiral highly functionalized zwitterionic bicyclic lactams starting from acyclic β-enaminoesters derived from (R)-(−)-2-phenylglycinol is described.

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