2016
DOI: 10.1016/j.bjm.2016.10.015
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Abstract: Most Escherichia coli strains live harmlessly in the intestines and rarely cause disease in healthy individuals. Nonetheless, a number of pathogenic strains can cause diarrhea or extraintestinal diseases both in healthy and immunocompromised individuals. Diarrheal illnesses are a severe public health problem and a major cause of morbidity and mortality in infants and young children, especially in developing countries. E. coli strains that cause diarrhea have evolved by acquiring, through horizontal gene transf… Show more

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Cited by 355 publications
(391 citation statements)
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References 417 publications
(505 reference statements)
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“…Diarrhoea is an important cause of mortality and morbidity in different areas of the world (developed and developing countries) and among all age groups [15].The epidemiology of enteric pathogens that cause diarrhoeasuggests that most infections are acquired from food, water,and hand contact and many diarrheal diseases can be prevented by simple rules of personal hygiene and safer foodpreparation [15,16]. In this study, from all stool samples analysed; DEC were detected in 14.7 %of cases, of which 8.5 % were from children under five yearsand 6.2 % from adults.…”
Section: Discussionmentioning
confidence: 99%
“…Diarrhoea is an important cause of mortality and morbidity in different areas of the world (developed and developing countries) and among all age groups [15].The epidemiology of enteric pathogens that cause diarrhoeasuggests that most infections are acquired from food, water,and hand contact and many diarrheal diseases can be prevented by simple rules of personal hygiene and safer foodpreparation [15,16]. In this study, from all stool samples analysed; DEC were detected in 14.7 %of cases, of which 8.5 % were from children under five yearsand 6.2 % from adults.…”
Section: Discussionmentioning
confidence: 99%
“…Severe symptoms may even lead to death [1][2][3][4]. Research into EHEC has mainly explored the development of attaching and effacing (A/E) intestinal lesions and the secretion of Shiga toxin in EHEC infection [5][6][7]. The protein EspF is one of the multifunctional effectors of A/E lesions induced by EHEC and enteropathogenic E. coli (EPEC).…”
mentioning
confidence: 99%
“…In order to identify different groups of E. coli, their associated specific primers were utilized, including bfp and eaeA for EPEC; lt and st for ETEC; ipaH and virF for EIEC; stx1, stx2, and eaeA for EHEC; and agg and aap for EAEC ( E. coli strains that were positive for aggR and/or aap genes were interpreted as being EAEC and those positive for stx1 and stx2, as STEC. The EIEC were those positive for virF and/or ipaH [7,8].…”
Section: Pcr To Detect Diarrheagenic E Coli Virulence Genesmentioning
confidence: 99%