B30. Mechanisms of Muscle Weakness in Critical Illness: Translating Basic Science to the Bedside 2012
DOI: 10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a2723
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Diaphragm Thickening Predicts Weaning From Mechanical Ventilation

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“…Δtdi% of ≤29.71 was found to be an indicator of weaning failure. These findings are consistent with the findings of Kawar et al [23], where they found that a Δtdi% >30% had a sensitivity of 95% and a specificity of 68% for extubation success. Similar results were also demonstrated by Farghaly and Hasan [24] and Alam et al [25], where tdi-end expiration out-performed RSBI.…”
Section: Discussionsupporting
confidence: 93%
“…Δtdi% of ≤29.71 was found to be an indicator of weaning failure. These findings are consistent with the findings of Kawar et al [23], where they found that a Δtdi% >30% had a sensitivity of 95% and a specificity of 68% for extubation success. Similar results were also demonstrated by Farghaly and Hasan [24] and Alam et al [25], where tdi-end expiration out-performed RSBI.…”
Section: Discussionsupporting
confidence: 93%
“…The measurement of the increase in diaphragmatic thickness during inspiration may be more accurate, with paralyzed diaphragms exhibiting less than 20% thickening during inspiration to total lung capacify (19). A preliminary report proposes that failure of the diaphragm to thicken at least 30% is strongly associated with weaning failure (20).…”
Section: Critical Care Medicinementioning
confidence: 99%