The oxidation state of fluids in Earth's mantle affects processes ranging from volcanism and the forma¬ tion of the crust, to the generation of many types of ore deposits. In general, the lowest oxidation state of the mantle (and hence its fluids) is defined by the buffer reaction 2FeO 2Fe + 02. However, unusual mineral assemblages that require far more reducing conditions are found in volcanic rocks from a variety of geotectonic settings, raising questions about how such conditions can be generated in the mantle. Examples from northern Israel, Tibet and Kamchatka suggest that interaction between magmas and methane-hydrogen fluids derived from the deep Earth have generated highly reducing conditions within some volcanic plumbing systems. Such systems appear to be related to the margins of tectonic plates, including zones of continent-continent collision and/or deep oceanic subduction, and transform faults extending deep (up to 200 km) into the Earth's mantle. This represents an important but previously unrecognized fluid-transfer process within the mantle. Foreword his paper is both a condensation and an expansion of the 2015 Clarke Memo¬ rial Lecture, given by WLG at Macquarie University in August 2015, which summa¬ rized recent work by the ARC Centre of Excellence for Core to Crust Fluid Systems (CCFS). We hope to provide both geolo¬ gists and non-specialists with a glimpse into some recent exciting developments in Earth Science, and to show how the integration of observations at scales from microns to moun¬ tain ranges can give us a new picture of how Earth works. We are trying to understand processes not previously recognized, and the paper therefore contains some "interesting" speculations, which we hope can generate (polite) discussion.