“…While purely speculative, we question whether caregivers, under certain circumstances where they have experienced a gradual increase in the amount of care-giving required or feel overly burdened by the care needs, may advocate against patients returning to PD after, for example, a peritonitis requiring catheter removal or an acute illness requiring temporary cessation of PD. Data from ongoing studies, such as PD outcomes and practice patterns study may help answer some of these questions, in particular whether the observed gradual increase in the number of patients with functional disability who now are managed using chronic PD, correlate with a gradual increase in PD technique failure rates, such as that seen over the last decade (21,(41)(42)(43)(44)(45).…”