This study investigates into the complex interplay among communication strategies, globalization, and socio-economic factors within the context of regional development, with a specific focus on Ukraine. Employing a mixed-methods approach, it seeks to investigate the profound impact of effective communication strategies on socio-cultural management and their contribution to regional growth in the era of globalization. The study combines quantitative data from regional development reports with stakeholders across various Ukrainian regions. A theoretical model, based on game theory and the Prisoner's Dilemma, is employed to examine strategic choices in communication, globalization integration, socioeconomic focus, infrastructure development, and cultural initiatives.Through an extensive analysis combining quantitative data derived from regional development reports with insights from stakeholders representing diverse Ukrainian regions, this research reveals that cooperative communication strategies, characterized by robust engagement, a balanced approach to globalization, equitable socio-economic development, strategic infrastructure investment, and active promotion of cultural initiatives, yield the most favourable outcomes for regional development.The key takeaway from this study is the paramount significance of inclusive and participatory approaches, effective communication strategies, and harmonious integration of globalization to foster sustainable regional development. Notably, tailored communication strategies exhibit a significant correlation with the success of socio-cultural initiatives, consequently exerting a positive influence on regional development. These encompass community engagement, cultural sensitivity, and adaptive information dissemination. In conclusion, comprehending and optimizing communication strategies emerge as critical imperatives for harnessing the benefits of globalization in the realm of regional development in Ukraine and analogous contexts.
