Dialkylation of acetophenones and acetophenone ethylene ketals with 1,8-bis(trimethylsilyl)-2,6-octadiene (BISTRO). Semi-empirical SCF studies of α-methoxy-α-methylbenzyl cations

Total synthesis of steroids and heterosteroids from BISTRO

“…In the past few years, Santelli and et al [50][51][52] have introduced 1,8-bis(trimethylsilyl)octa-2,6-diene (BISTRO) 1 and extensively studied its reactivity toward electrophiles. BISTRO is a readily available [35] and very convenient annulation reagent to form divinylcyclopentane derivatives [53][54][55][56][57].…”

Preparation of 4‐Arylcyclopentenes by Sequential Diallylation of Arylaldehydes and Ring‐Closing Metathesis

“…These compounds have seldom been prepared and usualy as by-products in the course of the Heck reaction of halobenzenes with cyclopentene. As part of our research program on allylsilane chemistry [preparation of 1-aryl-2,5-divinylcyclopentanes by double allylation of aryl aldehydes or corresponding acetals with 1,8-bis(trimethylsilyl)-2,6-octadiene (BISTRO)], [3] we report herein the diallylation of aryl aldehydes followed by a ringclosure metathesis. As part of our research program on allylsilane chemistry [preparation of 1-aryl-2,5-divinylcyclopentanes by double allylation of aryl aldehydes or corresponding acetals with 1,8-bis(trimethylsilyl)-2,6-octadiene (BISTRO)], [3] we report herein the diallylation of aryl aldehydes followed by a ringclosure metathesis.…”

A Very Short Synthesis of Steroids from 1,3-Butadiene and Benzocyclobutenes

“…In the past few years, we have introduced 1,8-bis(trimethylsilyl)octa-2,6-diene (BISTRO) 1 and extensively studied its reactivity toward electrophiles . BISTRO is a readily available and very convenient annulation reagent to form divinylcyclopentane derivatives . Acylation of 1 with methyl 3-chloroformylpropionate or succinic anhydride gave the (±)-spirolactone 2 as a single product in 80% yield …”