This article examines the topic of Dialectical Behavior Therapy (DBT) applied in college counseling centers. Trends in mental health issues on college campuses are briefly reviewed in support of the increased need for evidence-based treatment of severe mental health issues. The article next presents an overview of the standard DBT model and reviews research regarding DBT in college counseling centers, focusing on clinical outcomes and adaptations made for the college counseling setting. Finally, there is a discussion of implications for practice, barriers to implementation and outcome measurement, and areas for future research.There has been little research to date on the effectiveness of evidencebased treatments for severe and chronic mental health issues in the college counseling setting. In a survey of college counseling center directors, Gallagher (2013) found that 95% of directors reported concerns about students presenting with severe and complex mental health issues, including nonsuicidal self-injury (NSSI), crises requiring immediate intervention, eating disorders, psychiatric medication issues, and substance abuse. Lifetime prevalence rates for NSSI in college students is estimated to be between 11.