Diagnostisches Management des primären Megaureters

Younsi, Nina

doi:10.1007/s00120-020-01119-7

Cited by 2 publications

(2 citation statements)

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“…As mentioned earlier, megaureter may be caused by a structural or functional obstruction of the ureterovesical junction; it represents the second most likely cause of neonatal hydronephrosis (Younsi 2020). According to Merlini and Spina (2005), abnormality or delay in the development of the longitudinal muscle bundle and an increased amount of collagen in the distal ureter adjacent to the ureterovesical junction results in the formation of an aperistaltic segment that leads to functional obstruction.…”

Section: Discussionmentioning

confidence: 98%

“…Epidemiologically, occurrence of congenital primary megaureter (PM) is unclear; however, it is the second most common cause of neonatal hydronephrosis (Younsi 2020). A primary congenital megaureter means a dilatation of the ureter with a ureteric diameter ≥7 mm (normal 3-5 mm) due to a structural or functional obstruc-tion of the ureterovesical junction (Younsi 2020). The male to female ratio is nearly 4:1 and the left side is more often affected than right (1.6-4.5 times) (Braga et al, 2016).…”

Section: Megauretermentioning

confidence: 99%

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Megaureter and hydronephrosis: Consequences of ureteric dysfunction

Melovitz-Vasan,

McBride,

Huff

et al. 2023

Ital J Anat Embryol

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The prevalence of “megaureter” among children can be as high as 20-25% and can be bilateral or unilateral; in some cases, the contralateral kidney is either absent or dysplastic. Megaureters can be categorized as obstructed, refluxing, obstructed and refluxing, or neither obstructing nor refluxing. Megaureter is likely to either transiently or permanently involve the kidneys, resulting in hydronephrosis or other medullary and cortical derangement. During routine student dissection of an 86-year-old female donor who died of atherosclerotic cardiovascular disease, we observed the presence of large ureters on both kidneys with the right-side ureters comparatively much larger than the left side. The upper and lower lobes of the right kidney were drained by independent ureters, which were encased in a thin, membranous connective tissue structure. Additionally, we also observed thinning of the renal cortex, renal pelvis, and caliceal dilation with total loss of medulla and lack of corticomedullary delineation. Importantly, reproductive structures such as uterus, fallopian tubes, ovaries. cervix and vagina were normal. This paper, in addition to providing a description of what was observed on dissection, will discuss various causes, pathophysiology, and alterations in the matrix composition of the ureter and kidney.

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Section: Discussionmentioning

confidence: 98%