Diagnostics in cystic echinococcosis: Serology versus ultrasonography

Abstract

Background/Aims: Cystic echinococcosis (CE) is the most widespread zoonosis worldwide. The objective of the present study was to compare diagnostic methods in the work-up of suspected cystic echinococcosis of the liver. Materials and Methods: Data from a total of 68 patients were compiled and analyzed. Results: A diagnosis of cystic echinococcosis was made in 36.8% of patients. Broken down according to WHO criteria, patients with at least one echinococcus cyst were determined in 12.0% of cases to exhibit cysts consistent with stage 1 disease (CE1), while in 24.0%, cysts consistent with CE2 and CE3 were identified. CE4 and CE5 cysts were identified in 32.0% and 8.0% of patients, respectively. Solitary cysts were found in 60.0% of patients with cystic echinococcosis, while in patients with at least one cystic lesion, there were most often multiple cysts. The indirect hemagglutination test (IHA) and echinococcus-specific immunoglobulin E (IgE) concentration showed a higher sensitivity (60.9%, 68.4%) than did the enzyme-linked immunosorbent assay (ELISA) for Echinococcus multilocularis (Em2

Primary Hydatid Cyst of the Stomach: A Rare Case Report and Review of the Literature

“…Among all imaging modalities, ultrasonography is superior to both MRI and CT in visualization and evaluation of the morphology of liver cysts and hydatid cyst as in our case we didn't use MRI. We used U&S in first step [10]. In sensitivity rates of ultrasonography for diagnosis of hydatid cyst are (88% to 98%) and specificity are (93% to 100%) [10].…”

“…We used U&S in first step [10]. In sensitivity rates of ultrasonography for diagnosis of hydatid cyst are (88% to 98%) and specificity are (93% to 100%) [10]. Abdominal cystic lesions as pesudocyst of pancreas, spleen cysts, mesenteric cysts, ovarian cysts and lymphangioma, must be considered in the differential diagnosis [8].…”

Primary Hydatid Cyst of the Small Intestine: A Rare Case Report and Brief Review of the Literature

“…The combination of clinical, laboratory, and radiological findings help for a preliminary diagnosis. Among all imaging modalities, ultrasonography is superior to both MRI and CT in visualization and evaluation of the morphology of liver cysts and hydatid disease [7]. In the literature, very high sensitivity (88% to 98%) and specificity (93% to 100%) rates are given for ultrasonography in the diagnosis of hydatid disease [7].…”

Estudio epidemiológico de hidatidosis comparando los test de ELISA IgE y Western Blot en población de cinco provincias de la Región Lima. 2015

“…Una concordancia del 99% entre la ocurrencia de anticuerpos IgG e IgE demuestra que la mayoría de estos individuos expuestos producen en alguna medida ambos tipos de anticuerpos contra los antígenos del parásito. Sin embargo, hasta el momento se tiene la gran limitación de que en el caso de quistes íntegros o hialinos donde no hay liberación de antígenos (21) , ya sea de membrana o del fluido hidatídico, no es posible encontrar anticuerpos debido a la pobre o nula estimulación del sistema inmune y a que el diagnóstico confirmatorio finalmente se realiza con la valoración clínica de las imágenes como la ecografía o la resonancia magnética, que a nivel del hígado tiene características muy bien definidas de actividad según la clasificación de la OMS (22) .…”